Experimental evaluation of the effects of commercial additive (plant extracts) as an alternative to growth-promoting antibiotics in broiler chickens

Autores
Luna, María Julieta; Corti Isgro, Maite; Rosales Cavaglieri, Lorenzo Alejandro; Coniglio, María Valeria; Ortiz, María Eugenia; Cavaglieri, Lilia Reneé; Parada, Julian; Magnoli, Alejandra Paola
Año de publicación
2025
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background and Aim: The increasing prevalence of antibiotic-resistant pathogens necessitates the exploration of alternatives to growth-promoting antibiotics (GPAs) in poultry production. This study evaluated a commercial additive containing plant extracts (carvacrol and cinnamaldehyde) as a potential replacement for GPAs in broiler chickens, focusing on productive parameters, cecal microbiota composition, cecal volatile fatty acid (VFA) concentration, and small intestinal histomorphology. Materials and Methods: The study involved 100 one-day-old Cobb 500 broiler chickens, divided into two treatment groups: Group 1 (control) received a basal diet (BD) with avilamycin (100 g/T), and Group 2 received a BD with a phytogenic feed additive (PFA) containing 10% carvacrol and 10% cinnamaldehyde (100 g/Tn). Over 42 days, the study measured total weight gain (TWG), feed intake, feed conversion ratio (FCR), carcass yield, digestive tract length, intestinal histomorphometry, VFA concentration, and cecal microbiota composition. Results: The PFA-treated group showed a 1.67% improvement in TWG and a 5.7% improvement in FCR compared to the control. The digestive tract length increased by 20 cm with PFA supplementation. While no significant differences were observed in cecal microbiota counts and VFA concentrations, a trend toward increased lactic acid bacteria and VFA levels was noted. Histomorphological analysis indicated enhanced villus height and a higher villus height-to-crypt depth ratio in the PFA group. Conclusion: The findings suggest that carvacrol and cinnamaldehyde-based PFAs may serve as viable alternatives to GPAs, promoting growth performance and gut health in broiler chickens. Further research is needed to elucidate the underlying mechanisms of action and confirm these preliminary results in larger-scale studies.
Fil: Luna, María Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Corti Isgro, Maite. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal; Argentina
Fil: Rosales Cavaglieri, Lorenzo Alejandro. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología. Cátedra de Micología; Argentina
Fil: Coniglio, María Valeria. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Ortiz, María Eugenia. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Cavaglieri, Lilia Reneé. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología. Cátedra de Micología; Argentina
Fil: Parada, Julian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal; Argentina
Fil: Magnoli, Alejandra Paola. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Materia
Antibiotic alternatives
Broiler chickens
Carvacrol
Gut health
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/289661
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/289661
network_acronym_str CONICETDig
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network_name_str CONICET Digital (CONICET)
spelling Experimental evaluation of the effects of commercial additive (plant extracts) as an alternative to growth-promoting antibiotics in broiler chickensLuna, María JulietaCorti Isgro, MaiteRosales Cavaglieri, Lorenzo AlejandroConiglio, María ValeriaOrtiz, María EugeniaCavaglieri, Lilia ReneéParada, JulianMagnoli, Alejandra PaolaAntibiotic alternativesBroiler chickensCarvacrolGut healthhttps://purl.org/becyt/ford/4.3https://purl.org/becyt/ford/4Background and Aim: The increasing prevalence of antibiotic-resistant pathogens necessitates the exploration of alternatives to growth-promoting antibiotics (GPAs) in poultry production. This study evaluated a commercial additive containing plant extracts (carvacrol and cinnamaldehyde) as a potential replacement for GPAs in broiler chickens, focusing on productive parameters, cecal microbiota composition, cecal volatile fatty acid (VFA) concentration, and small intestinal histomorphology. Materials and Methods: The study involved 100 one-day-old Cobb 500 broiler chickens, divided into two treatment groups: Group 1 (control) received a basal diet (BD) with avilamycin (100 g/T), and Group 2 received a BD with a phytogenic feed additive (PFA) containing 10% carvacrol and 10% cinnamaldehyde (100 g/Tn). Over 42 days, the study measured total weight gain (TWG), feed intake, feed conversion ratio (FCR), carcass yield, digestive tract length, intestinal histomorphometry, VFA concentration, and cecal microbiota composition. Results: The PFA-treated group showed a 1.67% improvement in TWG and a 5.7% improvement in FCR compared to the control. The digestive tract length increased by 20 cm with PFA supplementation. While no significant differences were observed in cecal microbiota counts and VFA concentrations, a trend toward increased lactic acid bacteria and VFA levels was noted. Histomorphological analysis indicated enhanced villus height and a higher villus height-to-crypt depth ratio in the PFA group. Conclusion: The findings suggest that carvacrol and cinnamaldehyde-based PFAs may serve as viable alternatives to GPAs, promoting growth performance and gut health in broiler chickens. Further research is needed to elucidate the underlying mechanisms of action and confirm these preliminary results in larger-scale studies.Fil: Luna, María Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; ArgentinaFil: Corti Isgro, Maite. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal; ArgentinaFil: Rosales Cavaglieri, Lorenzo Alejandro. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología. Cátedra de Micología; ArgentinaFil: Coniglio, María Valeria. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; ArgentinaFil: Ortiz, María Eugenia. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; ArgentinaFil: Cavaglieri, Lilia Reneé. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología. Cátedra de Micología; ArgentinaFil: Parada, Julian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal; ArgentinaFil: Magnoli, Alejandra Paola. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; ArgentinaVeterinary World2025-03info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/289661Luna, María Julieta; Corti Isgro, Maite; Rosales Cavaglieri, Lorenzo Alejandro; Coniglio, María Valeria; Ortiz, María Eugenia; et al.; Experimental evaluation of the effects of commercial additive (plant extracts) as an alternative to growth-promoting antibiotics in broiler chickens; Veterinary World; Veterinary World; 18; 3; 3-2025; 636-6450972-89882231-0916CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://veterinaryworld.org/Vol.18/March-2025/11.phpinfo:eu-repo/semantics/altIdentifier/doi/10.14202/vetworld.2025.636-645info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-08-25T15:40:50Zoai:ri.conicet.gov.ar:11336/289661instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-08-25 15:40:50.395CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Experimental evaluation of the effects of commercial additive (plant extracts) as an alternative to growth-promoting antibiotics in broiler chickens
title Experimental evaluation of the effects of commercial additive (plant extracts) as an alternative to growth-promoting antibiotics in broiler chickens
spellingShingle Experimental evaluation of the effects of commercial additive (plant extracts) as an alternative to growth-promoting antibiotics in broiler chickens
Luna, María Julieta
Antibiotic alternatives
Broiler chickens
Carvacrol
Gut health
title_short Experimental evaluation of the effects of commercial additive (plant extracts) as an alternative to growth-promoting antibiotics in broiler chickens
title_full Experimental evaluation of the effects of commercial additive (plant extracts) as an alternative to growth-promoting antibiotics in broiler chickens
title_fullStr Experimental evaluation of the effects of commercial additive (plant extracts) as an alternative to growth-promoting antibiotics in broiler chickens
title_full_unstemmed Experimental evaluation of the effects of commercial additive (plant extracts) as an alternative to growth-promoting antibiotics in broiler chickens
title_sort Experimental evaluation of the effects of commercial additive (plant extracts) as an alternative to growth-promoting antibiotics in broiler chickens
dc.creator.none.fl_str_mv Luna, María Julieta
Corti Isgro, Maite
Rosales Cavaglieri, Lorenzo Alejandro
Coniglio, María Valeria
Ortiz, María Eugenia
Cavaglieri, Lilia Reneé
Parada, Julian
Magnoli, Alejandra Paola
author Luna, María Julieta
author_facet Luna, María Julieta
Corti Isgro, Maite
Rosales Cavaglieri, Lorenzo Alejandro
Coniglio, María Valeria
Ortiz, María Eugenia
Cavaglieri, Lilia Reneé
Parada, Julian
Magnoli, Alejandra Paola
author_role author
author2 Corti Isgro, Maite
Rosales Cavaglieri, Lorenzo Alejandro
Coniglio, María Valeria
Ortiz, María Eugenia
Cavaglieri, Lilia Reneé
Parada, Julian
Magnoli, Alejandra Paola
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Antibiotic alternatives
Broiler chickens
Carvacrol
Gut health
topic Antibiotic alternatives
Broiler chickens
Carvacrol
Gut health
purl_subject.fl_str_mv https://purl.org/becyt/ford/4.3
https://purl.org/becyt/ford/4
dc.description.none.fl_txt_mv Background and Aim: The increasing prevalence of antibiotic-resistant pathogens necessitates the exploration of alternatives to growth-promoting antibiotics (GPAs) in poultry production. This study evaluated a commercial additive containing plant extracts (carvacrol and cinnamaldehyde) as a potential replacement for GPAs in broiler chickens, focusing on productive parameters, cecal microbiota composition, cecal volatile fatty acid (VFA) concentration, and small intestinal histomorphology. Materials and Methods: The study involved 100 one-day-old Cobb 500 broiler chickens, divided into two treatment groups: Group 1 (control) received a basal diet (BD) with avilamycin (100 g/T), and Group 2 received a BD with a phytogenic feed additive (PFA) containing 10% carvacrol and 10% cinnamaldehyde (100 g/Tn). Over 42 days, the study measured total weight gain (TWG), feed intake, feed conversion ratio (FCR), carcass yield, digestive tract length, intestinal histomorphometry, VFA concentration, and cecal microbiota composition. Results: The PFA-treated group showed a 1.67% improvement in TWG and a 5.7% improvement in FCR compared to the control. The digestive tract length increased by 20 cm with PFA supplementation. While no significant differences were observed in cecal microbiota counts and VFA concentrations, a trend toward increased lactic acid bacteria and VFA levels was noted. Histomorphological analysis indicated enhanced villus height and a higher villus height-to-crypt depth ratio in the PFA group. Conclusion: The findings suggest that carvacrol and cinnamaldehyde-based PFAs may serve as viable alternatives to GPAs, promoting growth performance and gut health in broiler chickens. Further research is needed to elucidate the underlying mechanisms of action and confirm these preliminary results in larger-scale studies.
Fil: Luna, María Julieta. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Corti Isgro, Maite. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal; Argentina
Fil: Rosales Cavaglieri, Lorenzo Alejandro. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología. Cátedra de Micología; Argentina
Fil: Coniglio, María Valeria. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Ortiz, María Eugenia. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
Fil: Cavaglieri, Lilia Reneé. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Ciencias Exactas, Fisicoquímicas y Naturales. Departamento de Microbiología e Inmunología. Cátedra de Micología; Argentina
Fil: Parada, Julian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Patología Animal; Argentina
Fil: Magnoli, Alejandra Paola. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba; Argentina. Universidad Nacional de Río Cuarto. Facultad de Agronomía y Veterinaria. Departamento de Producción Animal; Argentina
description Background and Aim: The increasing prevalence of antibiotic-resistant pathogens necessitates the exploration of alternatives to growth-promoting antibiotics (GPAs) in poultry production. This study evaluated a commercial additive containing plant extracts (carvacrol and cinnamaldehyde) as a potential replacement for GPAs in broiler chickens, focusing on productive parameters, cecal microbiota composition, cecal volatile fatty acid (VFA) concentration, and small intestinal histomorphology. Materials and Methods: The study involved 100 one-day-old Cobb 500 broiler chickens, divided into two treatment groups: Group 1 (control) received a basal diet (BD) with avilamycin (100 g/T), and Group 2 received a BD with a phytogenic feed additive (PFA) containing 10% carvacrol and 10% cinnamaldehyde (100 g/Tn). Over 42 days, the study measured total weight gain (TWG), feed intake, feed conversion ratio (FCR), carcass yield, digestive tract length, intestinal histomorphometry, VFA concentration, and cecal microbiota composition. Results: The PFA-treated group showed a 1.67% improvement in TWG and a 5.7% improvement in FCR compared to the control. The digestive tract length increased by 20 cm with PFA supplementation. While no significant differences were observed in cecal microbiota counts and VFA concentrations, a trend toward increased lactic acid bacteria and VFA levels was noted. Histomorphological analysis indicated enhanced villus height and a higher villus height-to-crypt depth ratio in the PFA group. Conclusion: The findings suggest that carvacrol and cinnamaldehyde-based PFAs may serve as viable alternatives to GPAs, promoting growth performance and gut health in broiler chickens. Further research is needed to elucidate the underlying mechanisms of action and confirm these preliminary results in larger-scale studies.
publishDate 2025
dc.date.none.fl_str_mv 2025-03
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/289661
Luna, María Julieta; Corti Isgro, Maite; Rosales Cavaglieri, Lorenzo Alejandro; Coniglio, María Valeria; Ortiz, María Eugenia; et al.; Experimental evaluation of the effects of commercial additive (plant extracts) as an alternative to growth-promoting antibiotics in broiler chickens; Veterinary World; Veterinary World; 18; 3; 3-2025; 636-645
0972-8988
2231-0916
CONICET Digital
CONICET
url http://hdl.handle.net/11336/289661
identifier_str_mv Luna, María Julieta; Corti Isgro, Maite; Rosales Cavaglieri, Lorenzo Alejandro; Coniglio, María Valeria; Ortiz, María Eugenia; et al.; Experimental evaluation of the effects of commercial additive (plant extracts) as an alternative to growth-promoting antibiotics in broiler chickens; Veterinary World; Veterinary World; 18; 3; 3-2025; 636-645
0972-8988
2231-0916
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://veterinaryworld.org/Vol.18/March-2025/11.php
info:eu-repo/semantics/altIdentifier/doi/10.14202/vetworld.2025.636-645
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Veterinary World
publisher.none.fl_str_mv Veterinary World
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.265058

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