Enhancing tuberculosis treatment support: A thematic analysis of interactive messages in a digital adherence technology trial to identify needs, challenges, and strategies for impr...

Autores
Roberti, Javier Eugenio; Carmiol Rodríguez, Priscilla; Chan Liang, Enrique; Aguilar Vidrio, Omar Alfonso; Suyanto, Agnes A.; Sprecher, Jennifer; Rubinstein, Fernando Adrian; Iribarren, Sarah
Año de publicación
2025
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Background: Digital adherence technologies (DATs) offer promising solutions for monitoring and supporting adherence to complex treatment regimens, including tuberculosis (TB) treatment. However, better understanding is needed of how users engage with DATs and how engagement influences their effectiveness, particularly in real-world settings and among underserved populations.Objective: Assess user engagement with the Companion app within the Tuberculosis Treatment Support Tools (TB-TST) intervention and explore the types of interactions that promote treatment adherence and address patients' needs.Methods: Secure message threads (N = 255) were analyzed as part of a four-site pragmatic clinical trial evaluating the effectiveness of the TB-TST intervention. Pragmatic thematic analysis was applied to chat logs between patients and treatment supporters (TSs) to identify key themes related to application utilization, treatment adherence, technical challenges, and communication patterns.Results: Key themes that emerged included: experiences of living with TB; COVID-19 pandemic impact; symptom guidance, healthcare coordination, and treatment and intervention adherence and technical issues. Patients frequently sought advice on how to integrate TB treatment into their daily lives, manage side effects, and cope with emotional distress. The communication styles of TSs varied, with personalized and empathetic interactions leading to better patient acceptance. Technical issues and difficulties accessing phone credit and connectivity challenges were barriers to intervention adherence. Recommendations from this analysis emphasize the need for personalized communication, streamlined adherence reporting, timely symptom guidance, expanded mental health support, and improved healthcare coordination to strengthen the intervention.Conclusion: This study highlights the importance of personalized, empathetic communication, and reliable technology to enhance the effectiveness of DATs. Future DAT solutions should prioritize technological reliability and the human elements of care. Interventions must be adaptable, user-friendly, and capable of addressing diverse patient needs, including offering emotional support and empowering individuals with limited digital literacy.
Fil: Roberti, Javier Eugenio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina
Fil: Carmiol Rodríguez, Priscilla. University of Washington; Estados Unidos
Fil: Chan Liang, Enrique. University of Washington; Estados Unidos
Fil: Aguilar Vidrio, Omar Alfonso. University of Washington; Estados Unidos
Fil: Suyanto, Agnes A.. University of Washington; Estados Unidos
Fil: Sprecher, Jennifer. University of Washington; Estados Unidos
Fil: Rubinstein, Fernando Adrian. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Iribarren, Sarah. University of Washington; Estados Unidos
Materia
TUBERCULOSIS
DIGITAL TECHNOLOGY
ADHERENCE
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/291223
Acceder
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network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Enhancing tuberculosis treatment support: A thematic analysis of interactive messages in a digital adherence technology trial to identify needs, challenges, and strategies for improvementRoberti, Javier EugenioCarmiol Rodríguez, PriscillaChan Liang, EnriqueAguilar Vidrio, Omar AlfonsoSuyanto, Agnes A.Sprecher, JenniferRubinstein, Fernando AdrianIribarren, SarahTUBERCULOSISDIGITAL TECHNOLOGYADHERENCEhttps://purl.org/becyt/ford/3.2https://purl.org/becyt/ford/3Background: Digital adherence technologies (DATs) offer promising solutions for monitoring and supporting adherence to complex treatment regimens, including tuberculosis (TB) treatment. However, better understanding is needed of how users engage with DATs and how engagement influences their effectiveness, particularly in real-world settings and among underserved populations.Objective: Assess user engagement with the Companion app within the Tuberculosis Treatment Support Tools (TB-TST) intervention and explore the types of interactions that promote treatment adherence and address patients' needs.Methods: Secure message threads (N = 255) were analyzed as part of a four-site pragmatic clinical trial evaluating the effectiveness of the TB-TST intervention. Pragmatic thematic analysis was applied to chat logs between patients and treatment supporters (TSs) to identify key themes related to application utilization, treatment adherence, technical challenges, and communication patterns.Results: Key themes that emerged included: experiences of living with TB; COVID-19 pandemic impact; symptom guidance, healthcare coordination, and treatment and intervention adherence and technical issues. Patients frequently sought advice on how to integrate TB treatment into their daily lives, manage side effects, and cope with emotional distress. The communication styles of TSs varied, with personalized and empathetic interactions leading to better patient acceptance. Technical issues and difficulties accessing phone credit and connectivity challenges were barriers to intervention adherence. Recommendations from this analysis emphasize the need for personalized communication, streamlined adherence reporting, timely symptom guidance, expanded mental health support, and improved healthcare coordination to strengthen the intervention.Conclusion: This study highlights the importance of personalized, empathetic communication, and reliable technology to enhance the effectiveness of DATs. Future DAT solutions should prioritize technological reliability and the human elements of care. Interventions must be adaptable, user-friendly, and capable of addressing diverse patient needs, including offering emotional support and empowering individuals with limited digital literacy.Fil: Roberti, Javier Eugenio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; ArgentinaFil: Carmiol Rodríguez, Priscilla. University of Washington; Estados UnidosFil: Chan Liang, Enrique. University of Washington; Estados UnidosFil: Aguilar Vidrio, Omar Alfonso. University of Washington; Estados UnidosFil: Suyanto, Agnes A.. University of Washington; Estados UnidosFil: Sprecher, Jennifer. University of Washington; Estados UnidosFil: Rubinstein, Fernando Adrian. Instituto de Efectividad Clínica y Sanitaria; ArgentinaFil: Iribarren, Sarah. University of Washington; Estados UnidosPublic Library of Science2025-07info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/291223Roberti, Javier Eugenio; Carmiol Rodríguez, Priscilla; Chan Liang, Enrique; Aguilar Vidrio, Omar Alfonso; Suyanto, Agnes A.; et al.; Enhancing tuberculosis treatment support: A thematic analysis of interactive messages in a digital adherence technology trial to identify needs, challenges, and strategies for improvement; Public Library of Science; Plos One; 20; 7; 7-2025; 1-181932-6203CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://dx.plos.org/10.1371/journal.pone.0326492info:eu-repo/semantics/altIdentifier/doi/10.1371/journal.pone.0326492info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-08-25T15:02:20Zoai:ri.conicet.gov.ar:11336/291223instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-08-25 15:02:20.318CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Enhancing tuberculosis treatment support: A thematic analysis of interactive messages in a digital adherence technology trial to identify needs, challenges, and strategies for improvement
title Enhancing tuberculosis treatment support: A thematic analysis of interactive messages in a digital adherence technology trial to identify needs, challenges, and strategies for improvement
spellingShingle Enhancing tuberculosis treatment support: A thematic analysis of interactive messages in a digital adherence technology trial to identify needs, challenges, and strategies for improvement
Roberti, Javier Eugenio
TUBERCULOSIS
DIGITAL TECHNOLOGY
ADHERENCE
title_short Enhancing tuberculosis treatment support: A thematic analysis of interactive messages in a digital adherence technology trial to identify needs, challenges, and strategies for improvement
title_full Enhancing tuberculosis treatment support: A thematic analysis of interactive messages in a digital adherence technology trial to identify needs, challenges, and strategies for improvement
title_fullStr Enhancing tuberculosis treatment support: A thematic analysis of interactive messages in a digital adherence technology trial to identify needs, challenges, and strategies for improvement
title_full_unstemmed Enhancing tuberculosis treatment support: A thematic analysis of interactive messages in a digital adherence technology trial to identify needs, challenges, and strategies for improvement
title_sort Enhancing tuberculosis treatment support: A thematic analysis of interactive messages in a digital adherence technology trial to identify needs, challenges, and strategies for improvement
dc.creator.none.fl_str_mv Roberti, Javier Eugenio
Carmiol Rodríguez, Priscilla
Chan Liang, Enrique
Aguilar Vidrio, Omar Alfonso
Suyanto, Agnes A.
Sprecher, Jennifer
Rubinstein, Fernando Adrian
Iribarren, Sarah
author Roberti, Javier Eugenio
author_facet Roberti, Javier Eugenio
Carmiol Rodríguez, Priscilla
Chan Liang, Enrique
Aguilar Vidrio, Omar Alfonso
Suyanto, Agnes A.
Sprecher, Jennifer
Rubinstein, Fernando Adrian
Iribarren, Sarah
author_role author
author2 Carmiol Rodríguez, Priscilla
Chan Liang, Enrique
Aguilar Vidrio, Omar Alfonso
Suyanto, Agnes A.
Sprecher, Jennifer
Rubinstein, Fernando Adrian
Iribarren, Sarah
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv TUBERCULOSIS
DIGITAL TECHNOLOGY
ADHERENCE
topic TUBERCULOSIS
DIGITAL TECHNOLOGY
ADHERENCE
purl_subject.fl_str_mv https://purl.org/becyt/ford/3.2
https://purl.org/becyt/ford/3
dc.description.none.fl_txt_mv Background: Digital adherence technologies (DATs) offer promising solutions for monitoring and supporting adherence to complex treatment regimens, including tuberculosis (TB) treatment. However, better understanding is needed of how users engage with DATs and how engagement influences their effectiveness, particularly in real-world settings and among underserved populations.Objective: Assess user engagement with the Companion app within the Tuberculosis Treatment Support Tools (TB-TST) intervention and explore the types of interactions that promote treatment adherence and address patients' needs.Methods: Secure message threads (N = 255) were analyzed as part of a four-site pragmatic clinical trial evaluating the effectiveness of the TB-TST intervention. Pragmatic thematic analysis was applied to chat logs between patients and treatment supporters (TSs) to identify key themes related to application utilization, treatment adherence, technical challenges, and communication patterns.Results: Key themes that emerged included: experiences of living with TB; COVID-19 pandemic impact; symptom guidance, healthcare coordination, and treatment and intervention adherence and technical issues. Patients frequently sought advice on how to integrate TB treatment into their daily lives, manage side effects, and cope with emotional distress. The communication styles of TSs varied, with personalized and empathetic interactions leading to better patient acceptance. Technical issues and difficulties accessing phone credit and connectivity challenges were barriers to intervention adherence. Recommendations from this analysis emphasize the need for personalized communication, streamlined adherence reporting, timely symptom guidance, expanded mental health support, and improved healthcare coordination to strengthen the intervention.Conclusion: This study highlights the importance of personalized, empathetic communication, and reliable technology to enhance the effectiveness of DATs. Future DAT solutions should prioritize technological reliability and the human elements of care. Interventions must be adaptable, user-friendly, and capable of addressing diverse patient needs, including offering emotional support and empowering individuals with limited digital literacy.
Fil: Roberti, Javier Eugenio. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina
Fil: Carmiol Rodríguez, Priscilla. University of Washington; Estados Unidos
Fil: Chan Liang, Enrique. University of Washington; Estados Unidos
Fil: Aguilar Vidrio, Omar Alfonso. University of Washington; Estados Unidos
Fil: Suyanto, Agnes A.. University of Washington; Estados Unidos
Fil: Sprecher, Jennifer. University of Washington; Estados Unidos
Fil: Rubinstein, Fernando Adrian. Instituto de Efectividad Clínica y Sanitaria; Argentina
Fil: Iribarren, Sarah. University of Washington; Estados Unidos
description Background: Digital adherence technologies (DATs) offer promising solutions for monitoring and supporting adherence to complex treatment regimens, including tuberculosis (TB) treatment. However, better understanding is needed of how users engage with DATs and how engagement influences their effectiveness, particularly in real-world settings and among underserved populations.Objective: Assess user engagement with the Companion app within the Tuberculosis Treatment Support Tools (TB-TST) intervention and explore the types of interactions that promote treatment adherence and address patients' needs.Methods: Secure message threads (N = 255) were analyzed as part of a four-site pragmatic clinical trial evaluating the effectiveness of the TB-TST intervention. Pragmatic thematic analysis was applied to chat logs between patients and treatment supporters (TSs) to identify key themes related to application utilization, treatment adherence, technical challenges, and communication patterns.Results: Key themes that emerged included: experiences of living with TB; COVID-19 pandemic impact; symptom guidance, healthcare coordination, and treatment and intervention adherence and technical issues. Patients frequently sought advice on how to integrate TB treatment into their daily lives, manage side effects, and cope with emotional distress. The communication styles of TSs varied, with personalized and empathetic interactions leading to better patient acceptance. Technical issues and difficulties accessing phone credit and connectivity challenges were barriers to intervention adherence. Recommendations from this analysis emphasize the need for personalized communication, streamlined adherence reporting, timely symptom guidance, expanded mental health support, and improved healthcare coordination to strengthen the intervention.Conclusion: This study highlights the importance of personalized, empathetic communication, and reliable technology to enhance the effectiveness of DATs. Future DAT solutions should prioritize technological reliability and the human elements of care. Interventions must be adaptable, user-friendly, and capable of addressing diverse patient needs, including offering emotional support and empowering individuals with limited digital literacy.
publishDate 2025
dc.date.none.fl_str_mv 2025-07
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/291223
Roberti, Javier Eugenio; Carmiol Rodríguez, Priscilla; Chan Liang, Enrique; Aguilar Vidrio, Omar Alfonso; Suyanto, Agnes A.; et al.; Enhancing tuberculosis treatment support: A thematic analysis of interactive messages in a digital adherence technology trial to identify needs, challenges, and strategies for improvement; Public Library of Science; Plos One; 20; 7; 7-2025; 1-18
1932-6203
CONICET Digital
CONICET
url http://hdl.handle.net/11336/291223
identifier_str_mv Roberti, Javier Eugenio; Carmiol Rodríguez, Priscilla; Chan Liang, Enrique; Aguilar Vidrio, Omar Alfonso; Suyanto, Agnes A.; et al.; Enhancing tuberculosis treatment support: A thematic analysis of interactive messages in a digital adherence technology trial to identify needs, challenges, and strategies for improvement; Public Library of Science; Plos One; 20; 7; 7-2025; 1-18
1932-6203
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://dx.plos.org/10.1371/journal.pone.0326492
info:eu-repo/semantics/altIdentifier/doi/10.1371/journal.pone.0326492
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.24418

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