Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1
- Autores
- Rosende, Andres; Romero, Cesar; DiPette, Donald J.; Brettler, Jeffrey; Van der Stuyft, Patrick; Satheesh, Gautam; Perel, Pablo; Chapman, Niamh; Moran, Andrew E.; Schutte, Aletta E.; Sharman, James E.; Irazola, Vilma; Huffman, Mark D.; Campbell, Norm R. C.; Salam, Abdul; Lanas, Fernando; Coca, Antonio; Garcia Zamora, Sebastian; Ferreiro, Alejandro; Lopez Jaramillo, Patricio; Rico Fontalvo, Jorge; Ridley, Emily; Picone, Dean; Flood, David; Piñeiro, Daniel José; Ojeda, Carolina Neira; Rodriguez, Gonzalo; Wellmann, Irmgardt A.; Orias, Marcelo; Rivera, Marcela; Reyes, Matías Villatoro; Onuma, Oyere; Ramroop, Shaun; Khan, Taskeen; Gonzalez, Yamile Valdes; Barroso, Weimar Kunz Sebba; Plavnik, Frida L.; Zuniga, Eric; Grassani, Ana María; Tajer, Carlos; Zaidel, Ezequiel; Marin, Marcos J.; Cyr Philbert, Shana; Amorin, Ignacio; Diaz Aguilera, Miguel Angel; Bortolotto, Luiz; Avezum, Alvaro; Ribeiro, Antonio Luiz P.; Tobe, Sheldon; Aumala, Teresa; Angell, Sonia; Lavados, Pablo; Martins, Sheila Ouriques; Echeverri, Ana Munera; Jaffe, Marc G.; Prabhakaran, Dorairaj; Parati, Gianfranco; Zhang, Xin Hua; Rodgers, Anthony; Yusuf, Salim; Whelton, Paul K.; Ordunez, Pedro
- Año de publicación
- 2025
- Idioma
- inglés
- Tipo de recurso
- artículo
- Estado
- versión publicada
- Descripción
- Background: HEARTS in the Americas is the regional adaptation of the WHO Global HEARTS Initiative, aimed at helping countries enhance hypertension and cardiovascular disease (CVD) risk management in primary care settings. Its core implementation tool, the HEARTS Clinical Pathway, has been adopted by 28 countries. To improve the care of hypertension, diabetes, and chronic kidney disease (CKD), HEARTS 2.0 was developed as a three-phase process to integrate evidence-based interventions into a unified care pathway, ensuring consistency across fragmented guidelines. This paper focuses on Phase 1, highlighting targeted interventions to improve and update the HEARTS Clinical Pathway.Methods: First, the coordinating group defined the project´s scope, objectives, principles, methodological framework, and tools. Second, international experts from different disciplines proposed interventions to enhance the HEARTS Clinical Pathway. Third, the coordinating group harmonized these proposals into unique interventions. Fourth, experts appraised the appropriateness of the proposed interventions on a 1-to-9 scale using the adapted RAND/UCLA Appropriateness Method. Finally, interventions with a median score above 6 were deemed appropriate and selected as candidates to enhance the HEARTS Clinical Pathway.Results: Building on the existing HEARTS Clinical Pathway, 45 unique interventions were selected, including community-based screening, early detection and management of risk factors, lower blood pressure thresholds for diagnosing hypertension in high-CVD-risk patients, reinforcement of single-pill combination therapy, inclusion of sodium-glucose cotransporter-2 inhibitors for patients with diabetes, CKD, or heart failure, expanded roles for non-physician health workers in team-based care, and strengthened clinical documentation, monitoring, and evaluation.Conclusion: HEARTS 2.0 Phase 1 identifies key interventions to integrate and improve hypertension and cardiovascular-kidney-metabolic care within primary care, enabling their seamless incorporation into a unified and effective clinical pathway. This process will inform an update to the HEARTS Clinical Pathway, optimizing resources, reducing care fragmentation, improving care delivery, and advancing health equity, thereby supporting global efforts to combat the leading causes of death and disability.
Fil: Rosende, Andres. Pan American Health Organization; Estados Unidos
Fil: Romero, Cesar. University of Emory; Estados Unidos
Fil: DiPette, Donald J.. No especifíca;
Fil: Brettler, Jeffrey. Kaiser Permanente; Estados Unidos
Fil: Van der Stuyft, Patrick. Ghent University; Bélgica
Fil: Satheesh, Gautam. The George Institute For Global Health; Australia
Fil: Perel, Pablo. No especifíca;
Fil: Chapman, Niamh. University Of Sydney; Australia
Fil: Moran, Andrew E.. Columbia University; Estados Unidos
Fil: Schutte, Aletta E.. The George Institute For Global Health; Australia
Fil: Sharman, James E.. Menzies Institute For Medical Research; Australia
Fil: Irazola, Vilma. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina
Fil: Huffman, Mark D.. No especifíca;
Fil: Campbell, Norm R. C.. No especifíca;
Fil: Salam, Abdul. No especifíca;
Fil: Lanas, Fernando. No especifíca;
Fil: Coca, Antonio. No especifíca;
Fil: Garcia Zamora, Sebastian. No especifíca;
Fil: Ferreiro, Alejandro. No especifíca;
Fil: Lopez Jaramillo, Patricio. No especifíca;
Fil: Rico Fontalvo, Jorge. No especifíca;
Fil: Ridley, Emily. No especifíca;
Fil: Picone, Dean. No especifíca;
Fil: Flood, David. No especifíca;
Fil: Piñeiro, Daniel José. No especifíca;
Fil: Ojeda, Carolina Neira. No especifíca;
Fil: Rodriguez, Gonzalo. No especifíca;
Fil: Wellmann, Irmgardt A.. No especifíca;
Fil: Orias, Marcelo. No especifíca;
Fil: Rivera, Marcela. No especifíca;
Fil: Reyes, Matías Villatoro. No especifíca;
Fil: Onuma, Oyere. No especifíca;
Fil: Ramroop, Shaun. No especifíca;
Fil: Khan, Taskeen. No especifíca;
Fil: Gonzalez, Yamile Valdes. No especifíca;
Fil: Barroso, Weimar Kunz Sebba. No especifíca;
Fil: Plavnik, Frida L.. No especifíca;
Fil: Zuniga, Eric. No especifíca;
Fil: Grassani, Ana María. No especifíca;
Fil: Tajer, Carlos. No especifíca;
Fil: Zaidel, Ezequiel. No especifíca;
Fil: Marin, Marcos J.. No especifíca;
Fil: Cyr Philbert, Shana. No especifíca;
Fil: Amorin, Ignacio. No especifíca;
Fil: Diaz Aguilera, Miguel Angel. No especifíca;
Fil: Bortolotto, Luiz. No especifíca;
Fil: Avezum, Alvaro. No especifíca;
Fil: Ribeiro, Antonio Luiz P.. No especifíca;
Fil: Tobe, Sheldon. No especifíca;
Fil: Aumala, Teresa. No especifíca;
Fil: Angell, Sonia. No especifíca;
Fil: Lavados, Pablo. No especifíca;
Fil: Martins, Sheila Ouriques. No especifíca;
Fil: Echeverri, Ana Munera. No especifíca;
Fil: Jaffe, Marc G.. No especifíca;
Fil: Prabhakaran, Dorairaj. No especifíca;
Fil: Parati, Gianfranco. No especifíca;
Fil: Zhang, Xin Hua. No especifíca;
Fil: Rodgers, Anthony. No especifíca;
Fil: Yusuf, Salim. No especifíca;
Fil: Whelton, Paul K.. No especifíca;
Fil: Ordunez, Pedro. No especifíca; - Materia
-
Cardiovascular Diseases
Chronic
Primary Health Care
Renal Insufficiency
Stroke
diabetes mellitus
hypertension - Nivel de accesibilidad
- acceso abierto
- Condiciones de uso
- https://creativecommons.org/licenses/by/2.5/ar/
- Repositorio
.jpg)
- Institución
- Consejo Nacional de Investigaciones Científicas y Técnicas
- OAI Identificador
- oai:ri.conicet.gov.ar:11336/291158
Ver los metadatos del registro completo
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Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1Rosende, AndresRomero, CesarDiPette, Donald J.Brettler, JeffreyVan der Stuyft, PatrickSatheesh, GautamPerel, PabloChapman, NiamhMoran, Andrew E.Schutte, Aletta E.Sharman, James E.Irazola, VilmaHuffman, Mark D.Campbell, Norm R. C.Salam, AbdulLanas, FernandoCoca, AntonioGarcia Zamora, SebastianFerreiro, AlejandroLopez Jaramillo, PatricioRico Fontalvo, JorgeRidley, EmilyPicone, DeanFlood, DavidPiñeiro, Daniel JoséOjeda, Carolina NeiraRodriguez, GonzaloWellmann, Irmgardt A.Orias, MarceloRivera, MarcelaReyes, Matías VillatoroOnuma, OyereRamroop, ShaunKhan, TaskeenGonzalez, Yamile ValdesBarroso, Weimar Kunz SebbaPlavnik, Frida L.Zuniga, EricGrassani, Ana MaríaTajer, CarlosZaidel, EzequielMarin, Marcos J.Cyr Philbert, ShanaAmorin, IgnacioDiaz Aguilera, Miguel AngelBortolotto, LuizAvezum, AlvaroRibeiro, Antonio Luiz P.Tobe, SheldonAumala, TeresaAngell, SoniaLavados, PabloMartins, Sheila OuriquesEcheverri, Ana MuneraJaffe, Marc G.Prabhakaran, DorairajParati, GianfrancoZhang, Xin HuaRodgers, AnthonyYusuf, SalimWhelton, Paul K.Ordunez, PedroCardiovascular DiseasesChronicPrimary Health CareRenal InsufficiencyStrokediabetes mellitushypertensionhttps://purl.org/becyt/ford/3.3https://purl.org/becyt/ford/3Background: HEARTS in the Americas is the regional adaptation of the WHO Global HEARTS Initiative, aimed at helping countries enhance hypertension and cardiovascular disease (CVD) risk management in primary care settings. Its core implementation tool, the HEARTS Clinical Pathway, has been adopted by 28 countries. To improve the care of hypertension, diabetes, and chronic kidney disease (CKD), HEARTS 2.0 was developed as a three-phase process to integrate evidence-based interventions into a unified care pathway, ensuring consistency across fragmented guidelines. This paper focuses on Phase 1, highlighting targeted interventions to improve and update the HEARTS Clinical Pathway.Methods: First, the coordinating group defined the project´s scope, objectives, principles, methodological framework, and tools. Second, international experts from different disciplines proposed interventions to enhance the HEARTS Clinical Pathway. Third, the coordinating group harmonized these proposals into unique interventions. Fourth, experts appraised the appropriateness of the proposed interventions on a 1-to-9 scale using the adapted RAND/UCLA Appropriateness Method. Finally, interventions with a median score above 6 were deemed appropriate and selected as candidates to enhance the HEARTS Clinical Pathway.Results: Building on the existing HEARTS Clinical Pathway, 45 unique interventions were selected, including community-based screening, early detection and management of risk factors, lower blood pressure thresholds for diagnosing hypertension in high-CVD-risk patients, reinforcement of single-pill combination therapy, inclusion of sodium-glucose cotransporter-2 inhibitors for patients with diabetes, CKD, or heart failure, expanded roles for non-physician health workers in team-based care, and strengthened clinical documentation, monitoring, and evaluation.Conclusion: HEARTS 2.0 Phase 1 identifies key interventions to integrate and improve hypertension and cardiovascular-kidney-metabolic care within primary care, enabling their seamless incorporation into a unified and effective clinical pathway. This process will inform an update to the HEARTS Clinical Pathway, optimizing resources, reducing care fragmentation, improving care delivery, and advancing health equity, thereby supporting global efforts to combat the leading causes of death and disability.Fil: Rosende, Andres. Pan American Health Organization; Estados UnidosFil: Romero, Cesar. University of Emory; Estados UnidosFil: DiPette, Donald J.. No especifíca;Fil: Brettler, Jeffrey. Kaiser Permanente; Estados UnidosFil: Van der Stuyft, Patrick. Ghent University; BélgicaFil: Satheesh, Gautam. The George Institute For Global Health; AustraliaFil: Perel, Pablo. No especifíca;Fil: Chapman, Niamh. University Of Sydney; AustraliaFil: Moran, Andrew E.. Columbia University; Estados UnidosFil: Schutte, Aletta E.. The George Institute For Global Health; AustraliaFil: Sharman, James E.. Menzies Institute For Medical Research; AustraliaFil: Irazola, Vilma. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; ArgentinaFil: Huffman, Mark D.. No especifíca;Fil: Campbell, Norm R. C.. No especifíca;Fil: Salam, Abdul. No especifíca;Fil: Lanas, Fernando. No especifíca;Fil: Coca, Antonio. No especifíca;Fil: Garcia Zamora, Sebastian. No especifíca;Fil: Ferreiro, Alejandro. No especifíca;Fil: Lopez Jaramillo, Patricio. No especifíca;Fil: Rico Fontalvo, Jorge. No especifíca;Fil: Ridley, Emily. No especifíca;Fil: Picone, Dean. No especifíca;Fil: Flood, David. No especifíca;Fil: Piñeiro, Daniel José. No especifíca;Fil: Ojeda, Carolina Neira. No especifíca;Fil: Rodriguez, Gonzalo. No especifíca;Fil: Wellmann, Irmgardt A.. No especifíca;Fil: Orias, Marcelo. No especifíca;Fil: Rivera, Marcela. No especifíca;Fil: Reyes, Matías Villatoro. No especifíca;Fil: Onuma, Oyere. No especifíca;Fil: Ramroop, Shaun. No especifíca;Fil: Khan, Taskeen. No especifíca;Fil: Gonzalez, Yamile Valdes. No especifíca;Fil: Barroso, Weimar Kunz Sebba. No especifíca;Fil: Plavnik, Frida L.. No especifíca;Fil: Zuniga, Eric. No especifíca;Fil: Grassani, Ana María. No especifíca;Fil: Tajer, Carlos. No especifíca;Fil: Zaidel, Ezequiel. No especifíca;Fil: Marin, Marcos J.. No especifíca;Fil: Cyr Philbert, Shana. No especifíca;Fil: Amorin, Ignacio. No especifíca;Fil: Diaz Aguilera, Miguel Angel. No especifíca;Fil: Bortolotto, Luiz. No especifíca;Fil: Avezum, Alvaro. No especifíca;Fil: Ribeiro, Antonio Luiz P.. No especifíca;Fil: Tobe, Sheldon. No especifíca;Fil: Aumala, Teresa. No especifíca;Fil: Angell, Sonia. No especifíca;Fil: Lavados, Pablo. No especifíca;Fil: Martins, Sheila Ouriques. No especifíca;Fil: Echeverri, Ana Munera. No especifíca;Fil: Jaffe, Marc G.. No especifíca;Fil: Prabhakaran, Dorairaj. No especifíca;Fil: Parati, Gianfranco. No especifíca;Fil: Zhang, Xin Hua. No especifíca;Fil: Rodgers, Anthony. No especifíca;Fil: Yusuf, Salim. No especifíca;Fil: Whelton, Paul K.. No especifíca;Fil: Ordunez, Pedro. No especifíca;Ubiquity Press2025-05info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/291158Rosende, Andres; Romero, Cesar; DiPette, Donald J.; Brettler, Jeffrey; Van der Stuyft, Patrick; et al.; Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1; Ubiquity Press; Global Heart; 20; 1; 5-2025; 1-172211-81602211-8179CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://account.globalheartjournal.com/index.php/up-j-gh/article/view/1428info:eu-repo/semantics/altIdentifier/doi/10.5334/gh.1428info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-08-25T14:49:49Zoai:ri.conicet.gov.ar:11336/291158instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-08-25 14:49:50.186CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse |
| dc.title.none.fl_str_mv |
Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1 |
| title |
Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1 |
| spellingShingle |
Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1 Rosende, Andres Cardiovascular Diseases Chronic Primary Health Care Renal Insufficiency Stroke diabetes mellitus hypertension |
| title_short |
Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1 |
| title_full |
Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1 |
| title_fullStr |
Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1 |
| title_full_unstemmed |
Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1 |
| title_sort |
Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1 |
| dc.creator.none.fl_str_mv |
Rosende, Andres Romero, Cesar DiPette, Donald J. Brettler, Jeffrey Van der Stuyft, Patrick Satheesh, Gautam Perel, Pablo Chapman, Niamh Moran, Andrew E. Schutte, Aletta E. Sharman, James E. Irazola, Vilma Huffman, Mark D. Campbell, Norm R. C. Salam, Abdul Lanas, Fernando Coca, Antonio Garcia Zamora, Sebastian Ferreiro, Alejandro Lopez Jaramillo, Patricio Rico Fontalvo, Jorge Ridley, Emily Picone, Dean Flood, David Piñeiro, Daniel José Ojeda, Carolina Neira Rodriguez, Gonzalo Wellmann, Irmgardt A. Orias, Marcelo Rivera, Marcela Reyes, Matías Villatoro Onuma, Oyere Ramroop, Shaun Khan, Taskeen Gonzalez, Yamile Valdes Barroso, Weimar Kunz Sebba Plavnik, Frida L. Zuniga, Eric Grassani, Ana María Tajer, Carlos Zaidel, Ezequiel Marin, Marcos J. Cyr Philbert, Shana Amorin, Ignacio Diaz Aguilera, Miguel Angel Bortolotto, Luiz Avezum, Alvaro Ribeiro, Antonio Luiz P. Tobe, Sheldon Aumala, Teresa Angell, Sonia Lavados, Pablo Martins, Sheila Ouriques Echeverri, Ana Munera Jaffe, Marc G. Prabhakaran, Dorairaj Parati, Gianfranco Zhang, Xin Hua Rodgers, Anthony Yusuf, Salim Whelton, Paul K. Ordunez, Pedro |
| author |
Rosende, Andres |
| author_facet |
Rosende, Andres Romero, Cesar DiPette, Donald J. Brettler, Jeffrey Van der Stuyft, Patrick Satheesh, Gautam Perel, Pablo Chapman, Niamh Moran, Andrew E. Schutte, Aletta E. Sharman, James E. Irazola, Vilma Huffman, Mark D. Campbell, Norm R. C. Salam, Abdul Lanas, Fernando Coca, Antonio Garcia Zamora, Sebastian Ferreiro, Alejandro Lopez Jaramillo, Patricio Rico Fontalvo, Jorge Ridley, Emily Picone, Dean Flood, David Piñeiro, Daniel José Ojeda, Carolina Neira Rodriguez, Gonzalo Wellmann, Irmgardt A. Orias, Marcelo Rivera, Marcela Reyes, Matías Villatoro Onuma, Oyere Ramroop, Shaun Khan, Taskeen Gonzalez, Yamile Valdes Barroso, Weimar Kunz Sebba Plavnik, Frida L. Zuniga, Eric Grassani, Ana María Tajer, Carlos Zaidel, Ezequiel Marin, Marcos J. Cyr Philbert, Shana Amorin, Ignacio Diaz Aguilera, Miguel Angel Bortolotto, Luiz Avezum, Alvaro Ribeiro, Antonio Luiz P. Tobe, Sheldon Aumala, Teresa Angell, Sonia Lavados, Pablo Martins, Sheila Ouriques Echeverri, Ana Munera Jaffe, Marc G. Prabhakaran, Dorairaj Parati, Gianfranco Zhang, Xin Hua Rodgers, Anthony Yusuf, Salim Whelton, Paul K. Ordunez, Pedro |
| author_role |
author |
| author2 |
Romero, Cesar DiPette, Donald J. Brettler, Jeffrey Van der Stuyft, Patrick Satheesh, Gautam Perel, Pablo Chapman, Niamh Moran, Andrew E. Schutte, Aletta E. Sharman, James E. Irazola, Vilma Huffman, Mark D. Campbell, Norm R. C. Salam, Abdul Lanas, Fernando Coca, Antonio Garcia Zamora, Sebastian Ferreiro, Alejandro Lopez Jaramillo, Patricio Rico Fontalvo, Jorge Ridley, Emily Picone, Dean Flood, David Piñeiro, Daniel José Ojeda, Carolina Neira Rodriguez, Gonzalo Wellmann, Irmgardt A. Orias, Marcelo Rivera, Marcela Reyes, Matías Villatoro Onuma, Oyere Ramroop, Shaun Khan, Taskeen Gonzalez, Yamile Valdes Barroso, Weimar Kunz Sebba Plavnik, Frida L. Zuniga, Eric Grassani, Ana María Tajer, Carlos Zaidel, Ezequiel Marin, Marcos J. Cyr Philbert, Shana Amorin, Ignacio Diaz Aguilera, Miguel Angel Bortolotto, Luiz Avezum, Alvaro Ribeiro, Antonio Luiz P. Tobe, Sheldon Aumala, Teresa Angell, Sonia Lavados, Pablo Martins, Sheila Ouriques Echeverri, Ana Munera Jaffe, Marc G. Prabhakaran, Dorairaj Parati, Gianfranco Zhang, Xin Hua Rodgers, Anthony Yusuf, Salim Whelton, Paul K. Ordunez, Pedro |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.subject.none.fl_str_mv |
Cardiovascular Diseases Chronic Primary Health Care Renal Insufficiency Stroke diabetes mellitus hypertension |
| topic |
Cardiovascular Diseases Chronic Primary Health Care Renal Insufficiency Stroke diabetes mellitus hypertension |
| purl_subject.fl_str_mv |
https://purl.org/becyt/ford/3.3 https://purl.org/becyt/ford/3 |
| dc.description.none.fl_txt_mv |
Background: HEARTS in the Americas is the regional adaptation of the WHO Global HEARTS Initiative, aimed at helping countries enhance hypertension and cardiovascular disease (CVD) risk management in primary care settings. Its core implementation tool, the HEARTS Clinical Pathway, has been adopted by 28 countries. To improve the care of hypertension, diabetes, and chronic kidney disease (CKD), HEARTS 2.0 was developed as a three-phase process to integrate evidence-based interventions into a unified care pathway, ensuring consistency across fragmented guidelines. This paper focuses on Phase 1, highlighting targeted interventions to improve and update the HEARTS Clinical Pathway.Methods: First, the coordinating group defined the project´s scope, objectives, principles, methodological framework, and tools. Second, international experts from different disciplines proposed interventions to enhance the HEARTS Clinical Pathway. Third, the coordinating group harmonized these proposals into unique interventions. Fourth, experts appraised the appropriateness of the proposed interventions on a 1-to-9 scale using the adapted RAND/UCLA Appropriateness Method. Finally, interventions with a median score above 6 were deemed appropriate and selected as candidates to enhance the HEARTS Clinical Pathway.Results: Building on the existing HEARTS Clinical Pathway, 45 unique interventions were selected, including community-based screening, early detection and management of risk factors, lower blood pressure thresholds for diagnosing hypertension in high-CVD-risk patients, reinforcement of single-pill combination therapy, inclusion of sodium-glucose cotransporter-2 inhibitors for patients with diabetes, CKD, or heart failure, expanded roles for non-physician health workers in team-based care, and strengthened clinical documentation, monitoring, and evaluation.Conclusion: HEARTS 2.0 Phase 1 identifies key interventions to integrate and improve hypertension and cardiovascular-kidney-metabolic care within primary care, enabling their seamless incorporation into a unified and effective clinical pathway. This process will inform an update to the HEARTS Clinical Pathway, optimizing resources, reducing care fragmentation, improving care delivery, and advancing health equity, thereby supporting global efforts to combat the leading causes of death and disability. Fil: Rosende, Andres. Pan American Health Organization; Estados Unidos Fil: Romero, Cesar. University of Emory; Estados Unidos Fil: DiPette, Donald J.. No especifíca; Fil: Brettler, Jeffrey. Kaiser Permanente; Estados Unidos Fil: Van der Stuyft, Patrick. Ghent University; Bélgica Fil: Satheesh, Gautam. The George Institute For Global Health; Australia Fil: Perel, Pablo. No especifíca; Fil: Chapman, Niamh. University Of Sydney; Australia Fil: Moran, Andrew E.. Columbia University; Estados Unidos Fil: Schutte, Aletta E.. The George Institute For Global Health; Australia Fil: Sharman, James E.. Menzies Institute For Medical Research; Australia Fil: Irazola, Vilma. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Centro de Investigaciones en Epidemiología y Salud Pública. Instituto de Efectividad Clínica y Sanitaria. Centro de Investigaciones en Epidemiología y Salud Pública; Argentina Fil: Huffman, Mark D.. No especifíca; Fil: Campbell, Norm R. C.. No especifíca; Fil: Salam, Abdul. No especifíca; Fil: Lanas, Fernando. No especifíca; Fil: Coca, Antonio. No especifíca; Fil: Garcia Zamora, Sebastian. No especifíca; Fil: Ferreiro, Alejandro. No especifíca; Fil: Lopez Jaramillo, Patricio. No especifíca; Fil: Rico Fontalvo, Jorge. No especifíca; Fil: Ridley, Emily. No especifíca; Fil: Picone, Dean. No especifíca; Fil: Flood, David. No especifíca; Fil: Piñeiro, Daniel José. No especifíca; Fil: Ojeda, Carolina Neira. No especifíca; Fil: Rodriguez, Gonzalo. No especifíca; Fil: Wellmann, Irmgardt A.. No especifíca; Fil: Orias, Marcelo. No especifíca; Fil: Rivera, Marcela. No especifíca; Fil: Reyes, Matías Villatoro. No especifíca; Fil: Onuma, Oyere. No especifíca; Fil: Ramroop, Shaun. No especifíca; Fil: Khan, Taskeen. No especifíca; Fil: Gonzalez, Yamile Valdes. No especifíca; Fil: Barroso, Weimar Kunz Sebba. No especifíca; Fil: Plavnik, Frida L.. No especifíca; Fil: Zuniga, Eric. No especifíca; Fil: Grassani, Ana María. No especifíca; Fil: Tajer, Carlos. No especifíca; Fil: Zaidel, Ezequiel. No especifíca; Fil: Marin, Marcos J.. No especifíca; Fil: Cyr Philbert, Shana. No especifíca; Fil: Amorin, Ignacio. No especifíca; Fil: Diaz Aguilera, Miguel Angel. No especifíca; Fil: Bortolotto, Luiz. No especifíca; Fil: Avezum, Alvaro. No especifíca; Fil: Ribeiro, Antonio Luiz P.. No especifíca; Fil: Tobe, Sheldon. No especifíca; Fil: Aumala, Teresa. No especifíca; Fil: Angell, Sonia. No especifíca; Fil: Lavados, Pablo. No especifíca; Fil: Martins, Sheila Ouriques. No especifíca; Fil: Echeverri, Ana Munera. No especifíca; Fil: Jaffe, Marc G.. No especifíca; Fil: Prabhakaran, Dorairaj. No especifíca; Fil: Parati, Gianfranco. No especifíca; Fil: Zhang, Xin Hua. No especifíca; Fil: Rodgers, Anthony. No especifíca; Fil: Yusuf, Salim. No especifíca; Fil: Whelton, Paul K.. No especifíca; Fil: Ordunez, Pedro. No especifíca; |
| description |
Background: HEARTS in the Americas is the regional adaptation of the WHO Global HEARTS Initiative, aimed at helping countries enhance hypertension and cardiovascular disease (CVD) risk management in primary care settings. Its core implementation tool, the HEARTS Clinical Pathway, has been adopted by 28 countries. To improve the care of hypertension, diabetes, and chronic kidney disease (CKD), HEARTS 2.0 was developed as a three-phase process to integrate evidence-based interventions into a unified care pathway, ensuring consistency across fragmented guidelines. This paper focuses on Phase 1, highlighting targeted interventions to improve and update the HEARTS Clinical Pathway.Methods: First, the coordinating group defined the project´s scope, objectives, principles, methodological framework, and tools. Second, international experts from different disciplines proposed interventions to enhance the HEARTS Clinical Pathway. Third, the coordinating group harmonized these proposals into unique interventions. Fourth, experts appraised the appropriateness of the proposed interventions on a 1-to-9 scale using the adapted RAND/UCLA Appropriateness Method. Finally, interventions with a median score above 6 were deemed appropriate and selected as candidates to enhance the HEARTS Clinical Pathway.Results: Building on the existing HEARTS Clinical Pathway, 45 unique interventions were selected, including community-based screening, early detection and management of risk factors, lower blood pressure thresholds for diagnosing hypertension in high-CVD-risk patients, reinforcement of single-pill combination therapy, inclusion of sodium-glucose cotransporter-2 inhibitors for patients with diabetes, CKD, or heart failure, expanded roles for non-physician health workers in team-based care, and strengthened clinical documentation, monitoring, and evaluation.Conclusion: HEARTS 2.0 Phase 1 identifies key interventions to integrate and improve hypertension and cardiovascular-kidney-metabolic care within primary care, enabling their seamless incorporation into a unified and effective clinical pathway. This process will inform an update to the HEARTS Clinical Pathway, optimizing resources, reducing care fragmentation, improving care delivery, and advancing health equity, thereby supporting global efforts to combat the leading causes of death and disability. |
| publishDate |
2025 |
| dc.date.none.fl_str_mv |
2025-05 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion http://purl.org/coar/resource_type/c_6501 info:ar-repo/semantics/articulo |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
http://hdl.handle.net/11336/291158 Rosende, Andres; Romero, Cesar; DiPette, Donald J.; Brettler, Jeffrey; Van der Stuyft, Patrick; et al.; Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1; Ubiquity Press; Global Heart; 20; 1; 5-2025; 1-17 2211-8160 2211-8179 CONICET Digital CONICET |
| url |
http://hdl.handle.net/11336/291158 |
| identifier_str_mv |
Rosende, Andres; Romero, Cesar; DiPette, Donald J.; Brettler, Jeffrey; Van der Stuyft, Patrick; et al.; Candidate Interventions for Integrating Hypertension and Cardiovascular-Kidney-Metabolic Care in Primary Health Settings: HEARTS 2.0 Phase 1; Ubiquity Press; Global Heart; 20; 1; 5-2025; 1-17 2211-8160 2211-8179 CONICET Digital CONICET |
| dc.language.none.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
info:eu-repo/semantics/altIdentifier/url/https://account.globalheartjournal.com/index.php/up-j-gh/article/view/1428 info:eu-repo/semantics/altIdentifier/doi/10.5334/gh.1428 |
| dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess https://creativecommons.org/licenses/by/2.5/ar/ |
| eu_rights_str_mv |
openAccess |
| rights_invalid_str_mv |
https://creativecommons.org/licenses/by/2.5/ar/ |
| dc.format.none.fl_str_mv |
application/pdf application/pdf |
| dc.publisher.none.fl_str_mv |
Ubiquity Press |
| publisher.none.fl_str_mv |
Ubiquity Press |
| dc.source.none.fl_str_mv |
reponame:CONICET Digital (CONICET) instname:Consejo Nacional de Investigaciones Científicas y Técnicas |
| reponame_str |
CONICET Digital (CONICET) |
| collection |
CONICET Digital (CONICET) |
| instname_str |
Consejo Nacional de Investigaciones Científicas y Técnicas |
| repository.name.fl_str_mv |
CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas |
| repository.mail.fl_str_mv |
dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar |
| _version_ |
1874774738882002944 |
| score |
13.24418 |