Nanomaterials-Enhanced Electrochemical Biosensors for Epithelial Cancer Diagnosis: Recent Advances

Autores
Regiart, Daniel Matias Gaston; Gimenez, Alba Marina; Ortega Gomez, Francisco; Gómez, Carlos Germán; Sainz, Juan; Tortella Fuentes, Gonzalo Rodrigo; Fernández Baldo, Martín Alejandro
Año de publicación
2025
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
In recent years, the interest in electrochemical biosensors has been constantly growing for epithelial cancer diagnosis and prognosis. The incorporation of the different nanomaterials as metal nanoparticles, magnetic nanoparticles, carbon nanomaterials, Metal–Organic Frameworks (MOFs), and nanocomposites, along with specific monoclonal antibodies, and nucleic acids (aptamers) has improved both sensitivity and specificity in these methodologies. In this review, we have presented examples of electrochemical biosensors for the determination of different epithelial cancer biomarkers. Based on numerous reports in the recent literature, we highlight the use of single and multiplexed analytical platforms for the quantification of epithelial cancer biomarkers. In addition, we outline potential development pathways, current challenges, and future prospects in the field of electrochemical immuno-, apta-, and genosensors.
Fil: Regiart, Daniel Matias Gaston. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Gimenez, Alba Marina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Química. Área de Química Analítica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis; Argentina
Fil: Ortega Gomez, Francisco. Universidade de Sao Paulo; Brasil
Fil: Gómez, Carlos Germán. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; Argentina
Fil: Sainz, Juan. Universidad de Barcelona; España. Universidad de Granada; España
Fil: Tortella Fuentes, Gonzalo Rodrigo. Universidad de La Frontera; Chile
Fil: Fernández Baldo, Martín Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Materia
BIOSENSOR
ELECTROCHEMICAL
NANOMATERIAL
TUMOR BIOMARKER
CANCER DIAGNOSIS
REAL SAMPLES
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/290659
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/290659
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network_name_str CONICET Digital (CONICET)
spelling Nanomaterials-Enhanced Electrochemical Biosensors for Epithelial Cancer Diagnosis: Recent AdvancesRegiart, Daniel Matias GastonGimenez, Alba MarinaOrtega Gomez, FranciscoGómez, Carlos GermánSainz, JuanTortella Fuentes, Gonzalo RodrigoFernández Baldo, Martín AlejandroBIOSENSORELECTROCHEMICALNANOMATERIALTUMOR BIOMARKERCANCER DIAGNOSISREAL SAMPLEShttps://purl.org/becyt/ford/1.4https://purl.org/becyt/ford/1https://purl.org/becyt/ford/2.10https://purl.org/becyt/ford/2In recent years, the interest in electrochemical biosensors has been constantly growing for epithelial cancer diagnosis and prognosis. The incorporation of the different nanomaterials as metal nanoparticles, magnetic nanoparticles, carbon nanomaterials, Metal–Organic Frameworks (MOFs), and nanocomposites, along with specific monoclonal antibodies, and nucleic acids (aptamers) has improved both sensitivity and specificity in these methodologies. In this review, we have presented examples of electrochemical biosensors for the determination of different epithelial cancer biomarkers. Based on numerous reports in the recent literature, we highlight the use of single and multiplexed analytical platforms for the quantification of epithelial cancer biomarkers. In addition, we outline potential development pathways, current challenges, and future prospects in the field of electrochemical immuno-, apta-, and genosensors.Fil: Regiart, Daniel Matias Gaston. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; ArgentinaFil: Gimenez, Alba Marina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Química. Área de Química Analítica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis; ArgentinaFil: Ortega Gomez, Francisco. Universidade de Sao Paulo; BrasilFil: Gómez, Carlos Germán. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; ArgentinaFil: Sainz, Juan. Universidad de Barcelona; España. Universidad de Granada; EspañaFil: Tortella Fuentes, Gonzalo Rodrigo. Universidad de La Frontera; ChileFil: Fernández Baldo, Martín Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; ArgentinaMultidisciplinary Digital Publishing Institute2025-11-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/290659Regiart, Daniel Matias Gaston; Gimenez, Alba Marina; Ortega Gomez, Francisco; Gómez, Carlos Germán; Sainz, Juan; et al.; Nanomaterials-Enhanced Electrochemical Biosensors for Epithelial Cancer Diagnosis: Recent Advances; Multidisciplinary Digital Publishing Institute; Biosensors; 15; 12; 25-11-2025; 766-7992079-6374CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2079-6374/15/12/766info:eu-repo/semantics/altIdentifier/doi/10.3390/bios15120766info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-08-25T15:06:14Zoai:ri.conicet.gov.ar:11336/290659instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-08-25 15:06:14.69CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Nanomaterials-Enhanced Electrochemical Biosensors for Epithelial Cancer Diagnosis: Recent Advances
title Nanomaterials-Enhanced Electrochemical Biosensors for Epithelial Cancer Diagnosis: Recent Advances
spellingShingle Nanomaterials-Enhanced Electrochemical Biosensors for Epithelial Cancer Diagnosis: Recent Advances
Regiart, Daniel Matias Gaston
BIOSENSOR
ELECTROCHEMICAL
NANOMATERIAL
TUMOR BIOMARKER
CANCER DIAGNOSIS
REAL SAMPLES
title_short Nanomaterials-Enhanced Electrochemical Biosensors for Epithelial Cancer Diagnosis: Recent Advances
title_full Nanomaterials-Enhanced Electrochemical Biosensors for Epithelial Cancer Diagnosis: Recent Advances
title_fullStr Nanomaterials-Enhanced Electrochemical Biosensors for Epithelial Cancer Diagnosis: Recent Advances
title_full_unstemmed Nanomaterials-Enhanced Electrochemical Biosensors for Epithelial Cancer Diagnosis: Recent Advances
title_sort Nanomaterials-Enhanced Electrochemical Biosensors for Epithelial Cancer Diagnosis: Recent Advances
dc.creator.none.fl_str_mv Regiart, Daniel Matias Gaston
Gimenez, Alba Marina
Ortega Gomez, Francisco
Gómez, Carlos Germán
Sainz, Juan
Tortella Fuentes, Gonzalo Rodrigo
Fernández Baldo, Martín Alejandro
author Regiart, Daniel Matias Gaston
author_facet Regiart, Daniel Matias Gaston
Gimenez, Alba Marina
Ortega Gomez, Francisco
Gómez, Carlos Germán
Sainz, Juan
Tortella Fuentes, Gonzalo Rodrigo
Fernández Baldo, Martín Alejandro
author_role author
author2 Gimenez, Alba Marina
Ortega Gomez, Francisco
Gómez, Carlos Germán
Sainz, Juan
Tortella Fuentes, Gonzalo Rodrigo
Fernández Baldo, Martín Alejandro
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv BIOSENSOR
ELECTROCHEMICAL
NANOMATERIAL
TUMOR BIOMARKER
CANCER DIAGNOSIS
REAL SAMPLES
topic BIOSENSOR
ELECTROCHEMICAL
NANOMATERIAL
TUMOR BIOMARKER
CANCER DIAGNOSIS
REAL SAMPLES
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.4
https://purl.org/becyt/ford/1
https://purl.org/becyt/ford/2.10
https://purl.org/becyt/ford/2
dc.description.none.fl_txt_mv In recent years, the interest in electrochemical biosensors has been constantly growing for epithelial cancer diagnosis and prognosis. The incorporation of the different nanomaterials as metal nanoparticles, magnetic nanoparticles, carbon nanomaterials, Metal–Organic Frameworks (MOFs), and nanocomposites, along with specific monoclonal antibodies, and nucleic acids (aptamers) has improved both sensitivity and specificity in these methodologies. In this review, we have presented examples of electrochemical biosensors for the determination of different epithelial cancer biomarkers. Based on numerous reports in the recent literature, we highlight the use of single and multiplexed analytical platforms for the quantification of epithelial cancer biomarkers. In addition, we outline potential development pathways, current challenges, and future prospects in the field of electrochemical immuno-, apta-, and genosensors.
Fil: Regiart, Daniel Matias Gaston. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
Fil: Gimenez, Alba Marina. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Departamento de Química. Área de Química Analítica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis; Argentina
Fil: Ortega Gomez, Francisco. Universidade de Sao Paulo; Brasil
Fil: Gómez, Carlos Germán. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Investigaciones en Tecnología Química. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Investigaciones en Tecnología Química; Argentina
Fil: Sainz, Juan. Universidad de Barcelona; España. Universidad de Granada; España
Fil: Tortella Fuentes, Gonzalo Rodrigo. Universidad de La Frontera; Chile
Fil: Fernández Baldo, Martín Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia. Instituto de Química de San Luis; Argentina
description In recent years, the interest in electrochemical biosensors has been constantly growing for epithelial cancer diagnosis and prognosis. The incorporation of the different nanomaterials as metal nanoparticles, magnetic nanoparticles, carbon nanomaterials, Metal–Organic Frameworks (MOFs), and nanocomposites, along with specific monoclonal antibodies, and nucleic acids (aptamers) has improved both sensitivity and specificity in these methodologies. In this review, we have presented examples of electrochemical biosensors for the determination of different epithelial cancer biomarkers. Based on numerous reports in the recent literature, we highlight the use of single and multiplexed analytical platforms for the quantification of epithelial cancer biomarkers. In addition, we outline potential development pathways, current challenges, and future prospects in the field of electrochemical immuno-, apta-, and genosensors.
publishDate 2025
dc.date.none.fl_str_mv 2025-11-25
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/290659
Regiart, Daniel Matias Gaston; Gimenez, Alba Marina; Ortega Gomez, Francisco; Gómez, Carlos Germán; Sainz, Juan; et al.; Nanomaterials-Enhanced Electrochemical Biosensors for Epithelial Cancer Diagnosis: Recent Advances; Multidisciplinary Digital Publishing Institute; Biosensors; 15; 12; 25-11-2025; 766-799
2079-6374
CONICET Digital
CONICET
url http://hdl.handle.net/11336/290659
identifier_str_mv Regiart, Daniel Matias Gaston; Gimenez, Alba Marina; Ortega Gomez, Francisco; Gómez, Carlos Germán; Sainz, Juan; et al.; Nanomaterials-Enhanced Electrochemical Biosensors for Epithelial Cancer Diagnosis: Recent Advances; Multidisciplinary Digital Publishing Institute; Biosensors; 15; 12; 25-11-2025; 766-799
2079-6374
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2079-6374/15/12/766
info:eu-repo/semantics/altIdentifier/doi/10.3390/bios15120766
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
application/pdf
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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score 13.24418

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