Antarctic Bacteriophages: Their Ecological Role and Biotechnological Potential

Autores
Napolitano, Nicolas Antonio; Massot, Francisco; Quiroga, Cecilia; MacCormack, Walter P.; López, José Luis
Año de publicación
2025
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Viruses that infect bacteria (bacteriophages or phages) are the most abundant biological entities in thebiosphere. Phages play a central role in shaping microbial communities and regulating global biogeochemicalcycles. Two major biological cycles characterize phages: the lytic and the lysogenic cycles. This study focuseson the lysogenic cycle, in which phages integrate into the bacterial genome. The study of bacterium–phagesystems in Antarctic environments is of particular interest due to the extreme environmental conditionsunder which these interactions occur. Antarctic bacteria isolated from different habitats were investigatedto characterize their lysogenic viruses. Bizionia argentinensis, Rhodococcus spp. strain ADH, and Agreiaspp. were characterized both in silico and in vitro for the presence of integrated phages (prophages). Theseprophages harbor a genetic repertoire that may play a central role in host–environment interactions. Inaddition, some prophage-derived genes (including endolysins, enzymes that lyse bacterial cell walls) havepotential biotechnological applications. In particular, enzymes adapted to function at low temperaturescould be exploited for industrial use.
Fil: Napolitano, Nicolas Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Massot, Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Quiroga, Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; Argentina
Fil: MacCormack, Walter P.. Ministerio de Relaciones Exteriores, Comercio Interno y Culto. Dirección Nacional del Antártico. Instituto Antártico Argentino; Argentina
Fil: López, José Luis. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Materia
Evolution
Bacteriophages
Lysogeny
Genes of interest
Biotechnology
Antarctica
AntarcticTreaty
Antarctic Environmental Protection
Antarctic Tourism
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/284919
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/284919
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Antarctic Bacteriophages: Their Ecological Role and Biotechnological PotentialNapolitano, Nicolas AntonioMassot, FranciscoQuiroga, CeciliaMacCormack, Walter P.López, José LuisEvolutionBacteriophagesLysogenyGenes of interestBiotechnologyAntarcticaAntarcticTreatyAntarctic Environmental ProtectionAntarctic Tourismhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Viruses that infect bacteria (bacteriophages or phages) are the most abundant biological entities in thebiosphere. Phages play a central role in shaping microbial communities and regulating global biogeochemicalcycles. Two major biological cycles characterize phages: the lytic and the lysogenic cycles. This study focuseson the lysogenic cycle, in which phages integrate into the bacterial genome. The study of bacterium–phagesystems in Antarctic environments is of particular interest due to the extreme environmental conditionsunder which these interactions occur. Antarctic bacteria isolated from different habitats were investigatedto characterize their lysogenic viruses. Bizionia argentinensis, Rhodococcus spp. strain ADH, and Agreiaspp. were characterized both in silico and in vitro for the presence of integrated phages (prophages). Theseprophages harbor a genetic repertoire that may play a central role in host–environment interactions. Inaddition, some prophage-derived genes (including endolysins, enzymes that lyse bacterial cell walls) havepotential biotechnological applications. In particular, enzymes adapted to function at low temperaturescould be exploited for industrial use.Fil: Napolitano, Nicolas Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Massot, Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Quiroga, Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; ArgentinaFil: MacCormack, Walter P.. Ministerio de Relaciones Exteriores, Comercio Interno y Culto. Dirección Nacional del Antártico. Instituto Antártico Argentino; ArgentinaFil: López, José Luis. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFundación Agenda Antártica; Antarctic and Southern Ocean Coalition2025-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/284919Napolitano, Nicolas Antonio; Massot, Francisco; Quiroga, Cecilia; MacCormack, Walter P.; López, José Luis; Antarctic Bacteriophages: Their Ecological Role and Biotechnological Potential; Fundación Agenda Antártica; Antarctic and Southern Ocean Coalition; Journal of Antarctic Affaires; 11; 12-2025; 36-482451-5736CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://antarcticaffairs.org/wp-content/uploads/2026/02/03_2025FEB-2026-Journal-ENG.pdfinfo:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by-nc-sa/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-08-25T14:30:42Zoai:ri.conicet.gov.ar:11336/284919instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-08-25 14:30:42.662CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Antarctic Bacteriophages: Their Ecological Role and Biotechnological Potential
title Antarctic Bacteriophages: Their Ecological Role and Biotechnological Potential
spellingShingle Antarctic Bacteriophages: Their Ecological Role and Biotechnological Potential
Napolitano, Nicolas Antonio
Evolution
Bacteriophages
Lysogeny
Genes of interest
Biotechnology
Antarctica
AntarcticTreaty
Antarctic Environmental Protection
Antarctic Tourism
title_short Antarctic Bacteriophages: Their Ecological Role and Biotechnological Potential
title_full Antarctic Bacteriophages: Their Ecological Role and Biotechnological Potential
title_fullStr Antarctic Bacteriophages: Their Ecological Role and Biotechnological Potential
title_full_unstemmed Antarctic Bacteriophages: Their Ecological Role and Biotechnological Potential
title_sort Antarctic Bacteriophages: Their Ecological Role and Biotechnological Potential
dc.creator.none.fl_str_mv Napolitano, Nicolas Antonio
Massot, Francisco
Quiroga, Cecilia
MacCormack, Walter P.
López, José Luis
author Napolitano, Nicolas Antonio
author_facet Napolitano, Nicolas Antonio
Massot, Francisco
Quiroga, Cecilia
MacCormack, Walter P.
López, José Luis
author_role author
author2 Massot, Francisco
Quiroga, Cecilia
MacCormack, Walter P.
López, José Luis
author2_role author
author
author
author
dc.subject.none.fl_str_mv Evolution
Bacteriophages
Lysogeny
Genes of interest
Biotechnology
Antarctica
AntarcticTreaty
Antarctic Environmental Protection
Antarctic Tourism
topic Evolution
Bacteriophages
Lysogeny
Genes of interest
Biotechnology
Antarctica
AntarcticTreaty
Antarctic Environmental Protection
Antarctic Tourism
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Viruses that infect bacteria (bacteriophages or phages) are the most abundant biological entities in thebiosphere. Phages play a central role in shaping microbial communities and regulating global biogeochemicalcycles. Two major biological cycles characterize phages: the lytic and the lysogenic cycles. This study focuseson the lysogenic cycle, in which phages integrate into the bacterial genome. The study of bacterium–phagesystems in Antarctic environments is of particular interest due to the extreme environmental conditionsunder which these interactions occur. Antarctic bacteria isolated from different habitats were investigatedto characterize their lysogenic viruses. Bizionia argentinensis, Rhodococcus spp. strain ADH, and Agreiaspp. were characterized both in silico and in vitro for the presence of integrated phages (prophages). Theseprophages harbor a genetic repertoire that may play a central role in host–environment interactions. Inaddition, some prophage-derived genes (including endolysins, enzymes that lyse bacterial cell walls) havepotential biotechnological applications. In particular, enzymes adapted to function at low temperaturescould be exploited for industrial use.
Fil: Napolitano, Nicolas Antonio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Massot, Francisco. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
Fil: Quiroga, Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Investigaciones en Microbiología y Parasitología Médica. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones en Microbiología y Parasitología Médica; Argentina
Fil: MacCormack, Walter P.. Ministerio de Relaciones Exteriores, Comercio Interno y Culto. Dirección Nacional del Antártico. Instituto Antártico Argentino; Argentina
Fil: López, José Luis. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentina
description Viruses that infect bacteria (bacteriophages or phages) are the most abundant biological entities in thebiosphere. Phages play a central role in shaping microbial communities and regulating global biogeochemicalcycles. Two major biological cycles characterize phages: the lytic and the lysogenic cycles. This study focuseson the lysogenic cycle, in which phages integrate into the bacterial genome. The study of bacterium–phagesystems in Antarctic environments is of particular interest due to the extreme environmental conditionsunder which these interactions occur. Antarctic bacteria isolated from different habitats were investigatedto characterize their lysogenic viruses. Bizionia argentinensis, Rhodococcus spp. strain ADH, and Agreiaspp. were characterized both in silico and in vitro for the presence of integrated phages (prophages). Theseprophages harbor a genetic repertoire that may play a central role in host–environment interactions. Inaddition, some prophage-derived genes (including endolysins, enzymes that lyse bacterial cell walls) havepotential biotechnological applications. In particular, enzymes adapted to function at low temperaturescould be exploited for industrial use.
publishDate 2025
dc.date.none.fl_str_mv 2025-12
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/284919
Napolitano, Nicolas Antonio; Massot, Francisco; Quiroga, Cecilia; MacCormack, Walter P.; López, José Luis; Antarctic Bacteriophages: Their Ecological Role and Biotechnological Potential; Fundación Agenda Antártica; Antarctic and Southern Ocean Coalition; Journal of Antarctic Affaires; 11; 12-2025; 36-48
2451-5736
CONICET Digital
CONICET
url http://hdl.handle.net/11336/284919
identifier_str_mv Napolitano, Nicolas Antonio; Massot, Francisco; Quiroga, Cecilia; MacCormack, Walter P.; López, José Luis; Antarctic Bacteriophages: Their Ecological Role and Biotechnological Potential; Fundación Agenda Antártica; Antarctic and Southern Ocean Coalition; Journal of Antarctic Affaires; 11; 12-2025; 36-48
2451-5736
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/https://antarcticaffairs.org/wp-content/uploads/2026/02/03_2025FEB-2026-Journal-ENG.pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by-nc-sa/2.5/ar/
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Fundación Agenda Antártica; Antarctic and Southern Ocean Coalition
publisher.none.fl_str_mv Fundación Agenda Antártica; Antarctic and Southern Ocean Coalition
dc.source.none.fl_str_mv reponame:CONICET Digital (CONICET)
instname:Consejo Nacional de Investigaciones Científicas y Técnicas
reponame_str CONICET Digital (CONICET)
collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
_version_ 1874774031886974976
score 13.265058

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