Impact of Daily and Seasonal Variation on the Phytochemical Profile of Larrea cuneifolia in Northwestern Argentina

Autores
Barrera, Maria Celeste; Rosa, Mariana Daniela; Zampini, Iris Catiana; Isla, Maria Ines
Año de publicación
2025
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Larrea cuneifolia Cav. (common name: jarilla macho), is an endemic Argentinianmedicinal shrub that has traditionally been used by the Diaguita-Calchaquí communities in theMonte Desert region in northwestern Argentina. The aim of the present study was to analyze thephytochemical profile and biological activity of the aerial parts of jarilla collected in different placesthroughout the whole year, in different seasons and times of day, to determine the optimalharvesting conditions for promoting its medicinal use. The aerial parts were collected three times aday over the course of four seasons in eight L. cuneifolia populations. The total phenoliccompounds (TPC), total flavonoid (TF) content, total lignans (TL), sugars (S) and soluble proteins(SP) content were quantified by using spectrophotometric methods and HPLC-DAD. Antioxidantactivity was determined by using ABTS scavenging. Significant seasonal, diurnal and spatialvariation in the accumulation of TPC (52.61 to 113.52 mg GAE/g), TF (3.71 to 17.92 mg QE/g), TL(283 to 582 g NDHGAE/g); S (5.73 to 15.17 mg GE/g) and SP (36.75 to 103.10 mg BSAE/g) inaerial parts of L. cuneifolia were revealed. The highest concentrations of TPC and TF wererecorded in spring mornings. Maximum accumulation of nordihydroguaiaretic acid (291.8 ± 2.8 gNDHGAE/mg dry weight) and other lignans were also observed in spring. Heat map analysespinpoint Ampimpa (Site 1) as a site for jarilla sustainable harvesting, balancing high metabolitecontent with population abundance, especially in spring, when the highest antioxidant activity(SC 50 = 1.560 ± 0.021 g GAE/mL) coincides with increased phenols levels. These studies highlight the importance of integrating ecological and phytochemical data to defining harvesting strategies; collecting during spring mornings optimizes the yield of bioactive compounds, simultaneously minimizing ecological pressure. This study demonstrates how seasonal bioprospecting can inform pharmacological research and local development while safeguarding the endemic plant population.
Fil: Barrera, Maria Celeste. Universidad Nacional de Tucumán. Instituto de Bioprospección y Fisiología Vegetal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto de Bioprospección y Fisiología Vegetal; Argentina
Fil: Rosa, Mariana Daniela. Universidad Nacional de Tucumán. Instituto de Bioprospección y Fisiología Vegetal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto de Bioprospección y Fisiología Vegetal; Argentina
Fil: Zampini, Iris Catiana. Universidad Nacional de Tucumán. Instituto de Bioprospección y Fisiología Vegetal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto de Bioprospección y Fisiología Vegetal; Argentina
Fil: Isla, Maria Ines. Universidad Nacional de Tucumán. Instituto de Bioprospección y Fisiología Vegetal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto de Bioprospección y Fisiología Vegetal; Argentina
Materia
LARREA CUNEIFOLIA
SEASONAL AND DAILY VARIATION
TOTAL PHENOLIC COMPOUNDS
TOTAL FLAVONOIDS
NORDIHYDROGUAIARETIC ACID
ANTIOXIDANT CAPACITY
Nivel de accesibilidad
acceso abierto
Condiciones de uso
https://creativecommons.org/licenses/by/2.5/ar/
Repositorio
CONICET Digital (CONICET)
Institución
Consejo Nacional de Investigaciones Científicas y Técnicas
OAI Identificador
oai:ri.conicet.gov.ar:11336/291528
Acceder
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oai_identifier_str oai:ri.conicet.gov.ar:11336/291528
network_acronym_str CONICETDig
repository_id_str 3498
network_name_str CONICET Digital (CONICET)
spelling Impact of Daily and Seasonal Variation on the Phytochemical Profile of Larrea cuneifolia in Northwestern ArgentinaBarrera, Maria CelesteRosa, Mariana DanielaZampini, Iris CatianaIsla, Maria InesLARREA CUNEIFOLIASEASONAL AND DAILY VARIATIONTOTAL PHENOLIC COMPOUNDSTOTAL FLAVONOIDSNORDIHYDROGUAIARETIC ACIDANTIOXIDANT CAPACITYhttps://purl.org/becyt/ford/1.6https://purl.org/becyt/ford/1Larrea cuneifolia Cav. (common name: jarilla macho), is an endemic Argentinianmedicinal shrub that has traditionally been used by the Diaguita-Calchaquí communities in theMonte Desert region in northwestern Argentina. The aim of the present study was to analyze thephytochemical profile and biological activity of the aerial parts of jarilla collected in different placesthroughout the whole year, in different seasons and times of day, to determine the optimalharvesting conditions for promoting its medicinal use. The aerial parts were collected three times aday over the course of four seasons in eight L. cuneifolia populations. The total phenoliccompounds (TPC), total flavonoid (TF) content, total lignans (TL), sugars (S) and soluble proteins(SP) content were quantified by using spectrophotometric methods and HPLC-DAD. Antioxidantactivity was determined by using ABTS scavenging. Significant seasonal, diurnal and spatialvariation in the accumulation of TPC (52.61 to 113.52 mg GAE/g), TF (3.71 to 17.92 mg QE/g), TL(283 to 582 g NDHGAE/g); S (5.73 to 15.17 mg GE/g) and SP (36.75 to 103.10 mg BSAE/g) inaerial parts of L. cuneifolia were revealed. The highest concentrations of TPC and TF wererecorded in spring mornings. Maximum accumulation of nordihydroguaiaretic acid (291.8 ± 2.8 gNDHGAE/mg dry weight) and other lignans were also observed in spring. Heat map analysespinpoint Ampimpa (Site 1) as a site for jarilla sustainable harvesting, balancing high metabolitecontent with population abundance, especially in spring, when the highest antioxidant activity(SC 50 = 1.560 ± 0.021 g GAE/mL) coincides with increased phenols levels. These studies highlight the importance of integrating ecological and phytochemical data to defining harvesting strategies; collecting during spring mornings optimizes the yield of bioactive compounds, simultaneously minimizing ecological pressure. This study demonstrates how seasonal bioprospecting can inform pharmacological research and local development while safeguarding the endemic plant population.Fil: Barrera, Maria Celeste. Universidad Nacional de Tucumán. Instituto de Bioprospección y Fisiología Vegetal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto de Bioprospección y Fisiología Vegetal; ArgentinaFil: Rosa, Mariana Daniela. Universidad Nacional de Tucumán. Instituto de Bioprospección y Fisiología Vegetal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto de Bioprospección y Fisiología Vegetal; ArgentinaFil: Zampini, Iris Catiana. Universidad Nacional de Tucumán. Instituto de Bioprospección y Fisiología Vegetal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto de Bioprospección y Fisiología Vegetal; ArgentinaFil: Isla, Maria Ines. Universidad Nacional de Tucumán. Instituto de Bioprospección y Fisiología Vegetal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto de Bioprospección y Fisiología Vegetal; ArgentinaMDPI2025-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfapplication/pdfapplication/pdfapplication/pdfapplication/pdfhttp://hdl.handle.net/11336/291528Barrera, Maria Celeste; Rosa, Mariana Daniela; Zampini, Iris Catiana; Isla, Maria Ines; Impact of Daily and Seasonal Variation on the Phytochemical Profile of Larrea cuneifolia in Northwestern Argentina; MDPI; Plants; 14; 21; 10-2025; 1-162223-7747CONICET DigitalCONICETenginfo:eu-repo/semantics/altIdentifier/url/https://www.mdpi.com/2223-7747/14/21/3332info:eu-repo/semantics/altIdentifier/doi/10.3390/plants14213332info:eu-repo/semantics/openAccesshttps://creativecommons.org/licenses/by/2.5/ar/reponame:CONICET Digital (CONICET)instname:Consejo Nacional de Investigaciones Científicas y Técnicas2026-08-25T14:37:49Zoai:ri.conicet.gov.ar:11336/291528instacron:CONICETInstitucionalhttp://ri.conicet.gov.ar/Organismo científico-tecnológicoNo correspondehttp://ri.conicet.gov.ar/oai/requestdasensio@conicet.gov.ar; lcarlino@conicet.gov.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:34982026-08-25 14:37:49.44CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicasfalse
dc.title.none.fl_str_mv Impact of Daily and Seasonal Variation on the Phytochemical Profile of Larrea cuneifolia in Northwestern Argentina
title Impact of Daily and Seasonal Variation on the Phytochemical Profile of Larrea cuneifolia in Northwestern Argentina
spellingShingle Impact of Daily and Seasonal Variation on the Phytochemical Profile of Larrea cuneifolia in Northwestern Argentina
Barrera, Maria Celeste
LARREA CUNEIFOLIA
SEASONAL AND DAILY VARIATION
TOTAL PHENOLIC COMPOUNDS
TOTAL FLAVONOIDS
NORDIHYDROGUAIARETIC ACID
ANTIOXIDANT CAPACITY
title_short Impact of Daily and Seasonal Variation on the Phytochemical Profile of Larrea cuneifolia in Northwestern Argentina
title_full Impact of Daily and Seasonal Variation on the Phytochemical Profile of Larrea cuneifolia in Northwestern Argentina
title_fullStr Impact of Daily and Seasonal Variation on the Phytochemical Profile of Larrea cuneifolia in Northwestern Argentina
title_full_unstemmed Impact of Daily and Seasonal Variation on the Phytochemical Profile of Larrea cuneifolia in Northwestern Argentina
title_sort Impact of Daily and Seasonal Variation on the Phytochemical Profile of Larrea cuneifolia in Northwestern Argentina
dc.creator.none.fl_str_mv Barrera, Maria Celeste
Rosa, Mariana Daniela
Zampini, Iris Catiana
Isla, Maria Ines
author Barrera, Maria Celeste
author_facet Barrera, Maria Celeste
Rosa, Mariana Daniela
Zampini, Iris Catiana
Isla, Maria Ines
author_role author
author2 Rosa, Mariana Daniela
Zampini, Iris Catiana
Isla, Maria Ines
author2_role author
author
author
dc.subject.none.fl_str_mv LARREA CUNEIFOLIA
SEASONAL AND DAILY VARIATION
TOTAL PHENOLIC COMPOUNDS
TOTAL FLAVONOIDS
NORDIHYDROGUAIARETIC ACID
ANTIOXIDANT CAPACITY
topic LARREA CUNEIFOLIA
SEASONAL AND DAILY VARIATION
TOTAL PHENOLIC COMPOUNDS
TOTAL FLAVONOIDS
NORDIHYDROGUAIARETIC ACID
ANTIOXIDANT CAPACITY
purl_subject.fl_str_mv https://purl.org/becyt/ford/1.6
https://purl.org/becyt/ford/1
dc.description.none.fl_txt_mv Larrea cuneifolia Cav. (common name: jarilla macho), is an endemic Argentinianmedicinal shrub that has traditionally been used by the Diaguita-Calchaquí communities in theMonte Desert region in northwestern Argentina. The aim of the present study was to analyze thephytochemical profile and biological activity of the aerial parts of jarilla collected in different placesthroughout the whole year, in different seasons and times of day, to determine the optimalharvesting conditions for promoting its medicinal use. The aerial parts were collected three times aday over the course of four seasons in eight L. cuneifolia populations. The total phenoliccompounds (TPC), total flavonoid (TF) content, total lignans (TL), sugars (S) and soluble proteins(SP) content were quantified by using spectrophotometric methods and HPLC-DAD. Antioxidantactivity was determined by using ABTS scavenging. Significant seasonal, diurnal and spatialvariation in the accumulation of TPC (52.61 to 113.52 mg GAE/g), TF (3.71 to 17.92 mg QE/g), TL(283 to 582 g NDHGAE/g); S (5.73 to 15.17 mg GE/g) and SP (36.75 to 103.10 mg BSAE/g) inaerial parts of L. cuneifolia were revealed. The highest concentrations of TPC and TF wererecorded in spring mornings. Maximum accumulation of nordihydroguaiaretic acid (291.8 ± 2.8 gNDHGAE/mg dry weight) and other lignans were also observed in spring. Heat map analysespinpoint Ampimpa (Site 1) as a site for jarilla sustainable harvesting, balancing high metabolitecontent with population abundance, especially in spring, when the highest antioxidant activity(SC 50 = 1.560 ± 0.021 g GAE/mL) coincides with increased phenols levels. These studies highlight the importance of integrating ecological and phytochemical data to defining harvesting strategies; collecting during spring mornings optimizes the yield of bioactive compounds, simultaneously minimizing ecological pressure. This study demonstrates how seasonal bioprospecting can inform pharmacological research and local development while safeguarding the endemic plant population.
Fil: Barrera, Maria Celeste. Universidad Nacional de Tucumán. Instituto de Bioprospección y Fisiología Vegetal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto de Bioprospección y Fisiología Vegetal; Argentina
Fil: Rosa, Mariana Daniela. Universidad Nacional de Tucumán. Instituto de Bioprospección y Fisiología Vegetal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto de Bioprospección y Fisiología Vegetal; Argentina
Fil: Zampini, Iris Catiana. Universidad Nacional de Tucumán. Instituto de Bioprospección y Fisiología Vegetal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto de Bioprospección y Fisiología Vegetal; Argentina
Fil: Isla, Maria Ines. Universidad Nacional de Tucumán. Instituto de Bioprospección y Fisiología Vegetal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet Noa Sur. Instituto de Bioprospección y Fisiología Vegetal; Argentina
description Larrea cuneifolia Cav. (common name: jarilla macho), is an endemic Argentinianmedicinal shrub that has traditionally been used by the Diaguita-Calchaquí communities in theMonte Desert region in northwestern Argentina. The aim of the present study was to analyze thephytochemical profile and biological activity of the aerial parts of jarilla collected in different placesthroughout the whole year, in different seasons and times of day, to determine the optimalharvesting conditions for promoting its medicinal use. The aerial parts were collected three times aday over the course of four seasons in eight L. cuneifolia populations. The total phenoliccompounds (TPC), total flavonoid (TF) content, total lignans (TL), sugars (S) and soluble proteins(SP) content were quantified by using spectrophotometric methods and HPLC-DAD. Antioxidantactivity was determined by using ABTS scavenging. Significant seasonal, diurnal and spatialvariation in the accumulation of TPC (52.61 to 113.52 mg GAE/g), TF (3.71 to 17.92 mg QE/g), TL(283 to 582 g NDHGAE/g); S (5.73 to 15.17 mg GE/g) and SP (36.75 to 103.10 mg BSAE/g) inaerial parts of L. cuneifolia were revealed. The highest concentrations of TPC and TF wererecorded in spring mornings. Maximum accumulation of nordihydroguaiaretic acid (291.8 ± 2.8 gNDHGAE/mg dry weight) and other lignans were also observed in spring. Heat map analysespinpoint Ampimpa (Site 1) as a site for jarilla sustainable harvesting, balancing high metabolitecontent with population abundance, especially in spring, when the highest antioxidant activity(SC 50 = 1.560 ± 0.021 g GAE/mL) coincides with increased phenols levels. These studies highlight the importance of integrating ecological and phytochemical data to defining harvesting strategies; collecting during spring mornings optimizes the yield of bioactive compounds, simultaneously minimizing ecological pressure. This study demonstrates how seasonal bioprospecting can inform pharmacological research and local development while safeguarding the endemic plant population.
publishDate 2025
dc.date.none.fl_str_mv 2025-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11336/291528
Barrera, Maria Celeste; Rosa, Mariana Daniela; Zampini, Iris Catiana; Isla, Maria Ines; Impact of Daily and Seasonal Variation on the Phytochemical Profile of Larrea cuneifolia in Northwestern Argentina; MDPI; Plants; 14; 21; 10-2025; 1-16
2223-7747
CONICET Digital
CONICET
url http://hdl.handle.net/11336/291528
identifier_str_mv Barrera, Maria Celeste; Rosa, Mariana Daniela; Zampini, Iris Catiana; Isla, Maria Ines; Impact of Daily and Seasonal Variation on the Phytochemical Profile of Larrea cuneifolia in Northwestern Argentina; MDPI; Plants; 14; 21; 10-2025; 1-16
2223-7747
CONICET Digital
CONICET
dc.language.none.fl_str_mv eng
language eng
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info:eu-repo/semantics/altIdentifier/doi/10.3390/plants14213332
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
https://creativecommons.org/licenses/by/2.5/ar/
eu_rights_str_mv openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/2.5/ar/
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dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
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collection CONICET Digital (CONICET)
instname_str Consejo Nacional de Investigaciones Científicas y Técnicas
repository.name.fl_str_mv CONICET Digital (CONICET) - Consejo Nacional de Investigaciones Científicas y Técnicas
repository.mail.fl_str_mv dasensio@conicet.gov.ar; lcarlino@conicet.gov.ar
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