Use of pour-on formulations of fluralaner in prophylactic treatments against Cochliomyia hominivorax in newborn calves under extensive grazing systems

Autores
Gamietea, Ignacio José; Rossner, Maria Victoria; Lifschitz, Adrian Luis; Anziani, Oscar Sergio; Nava, Santiago
Año de publicación
2026
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The aim of this study was to evaluate the efficacy of pour-on fluralaner formulations for the prevention of cutaneous myiasis caused by Cochliomyia hominivorax in newborn calves under field conditions. Three field trials were conducted in Argentina, including subtropical and temperate regions. In Trial 1, calves with unhealed navels were assigned to two fluralaner-treated groups with different commercial pour-on formulations and an untreated control group. In Trial 2, two groups of newborn calves were treated either with fluralaner pour-on or injectable doramectin. Trial 3, where 84 calves were also treated with a pour-on formulation of fluralaner, was performed in an island livestock farming systems located along the Paraná River, where extensive grazing conditions are extreme, and the operational difficulties associated with providing meticulous animal husbandry practices to prevent parasitic diseases in cattle are amplified. Animals were monitored daily for the occurrence of myiasis. In Trial 1, no cases of myiasis were recorded in fluralaner-treated calves, whereas all control animals became infested. In Trial 2, no infestations were observed in the fluralaner-treated group, while myiasis was recorded in 3.5% of calves treated with doramectin. In Trial 3, the prevalence of myiasis in fluralaner-treated calves was 7.1%, with most cases associated with treatments applied under rainy conditions. In contrast, a prevalence of 34.5% was recorded in the previous year in the same herd when treatment consisted of insecticidal formulations based on organophosphates and pyrethroid. No adverse effects associated with fluralaner treatment were observed in all treated calves. These results demonstrate the high efficacy of fluralaner pour-on formulations for the prevention of C. hominivorax myiasis in newborn calves under extensive production systems.
EEA San Pedro
Fil: Gamietea, Ignacio José. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria San Pedro. Agencia de Extensión San Pedro; Argentina
Fil: Rossner, Maria Victoria. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez; Argentina
Fil: Lifschitz, Adrian. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Centro de Investigación Veterinaria de Tandil (CIVETAN). Laboratorio de Farmacología; Argentina.
Fil: Lifschitz, Adrian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigación Veterinaria de Tandil (CIVETAN); Argentina
Fil: Anziani, Oscar S. Universidad Católica de Córdoba. Facultad de Ciencias Agropecuarias; Argentina
Fil: Nava, Santiago. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina
Fil: Nava, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina
Fil: Nava, Santiago. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina
Fuente
Tropical Animal Health and Production 58 : article number 591. (October 2026)
Materia
Ganado Bovino
Ternero
Parásitos
Miasis
Control de Enfermedades
Manejo de Parásitos
Ganadería Extensiva
Cattle
Calves
Cochliomyia hominivorax
Parasites
Myiasis
Diseases Control
Parasite Control
Extensive Husbandry
Nivel de accesibilidad
acceso restringido
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/28132
Acceder
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oai_identifier_str oai:localhost:20.500.12123/28132
network_acronym_str INTADig
repository_id_str l
network_name_str INTA Digital (INTA)
spelling Use of pour-on formulations of fluralaner in prophylactic treatments against Cochliomyia hominivorax in newborn calves under extensive grazing systemsGamietea, Ignacio JoséRossner, Maria VictoriaLifschitz, Adrian LuisAnziani, Oscar SergioNava, SantiagoGanado BovinoTerneroParásitosMiasisControl de EnfermedadesManejo de ParásitosGanadería ExtensivaCattleCalvesCochliomyia hominivoraxParasitesMyiasisDiseases ControlParasite ControlExtensive HusbandryThe aim of this study was to evaluate the efficacy of pour-on fluralaner formulations for the prevention of cutaneous myiasis caused by Cochliomyia hominivorax in newborn calves under field conditions. Three field trials were conducted in Argentina, including subtropical and temperate regions. In Trial 1, calves with unhealed navels were assigned to two fluralaner-treated groups with different commercial pour-on formulations and an untreated control group. In Trial 2, two groups of newborn calves were treated either with fluralaner pour-on or injectable doramectin. Trial 3, where 84 calves were also treated with a pour-on formulation of fluralaner, was performed in an island livestock farming systems located along the Paraná River, where extensive grazing conditions are extreme, and the operational difficulties associated with providing meticulous animal husbandry practices to prevent parasitic diseases in cattle are amplified. Animals were monitored daily for the occurrence of myiasis. In Trial 1, no cases of myiasis were recorded in fluralaner-treated calves, whereas all control animals became infested. In Trial 2, no infestations were observed in the fluralaner-treated group, while myiasis was recorded in 3.5% of calves treated with doramectin. In Trial 3, the prevalence of myiasis in fluralaner-treated calves was 7.1%, with most cases associated with treatments applied under rainy conditions. In contrast, a prevalence of 34.5% was recorded in the previous year in the same herd when treatment consisted of insecticidal formulations based on organophosphates and pyrethroid. No adverse effects associated with fluralaner treatment were observed in all treated calves. These results demonstrate the high efficacy of fluralaner pour-on formulations for the prevention of C. hominivorax myiasis in newborn calves under extensive production systems.EEA San PedroFil: Gamietea, Ignacio José. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria San Pedro. Agencia de Extensión San Pedro; ArgentinaFil: Rossner, Maria Victoria. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez; ArgentinaFil: Lifschitz, Adrian. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Centro de Investigación Veterinaria de Tandil (CIVETAN). Laboratorio de Farmacología; Argentina.Fil: Lifschitz, Adrian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigación Veterinaria de Tandil (CIVETAN); ArgentinaFil: Anziani, Oscar S. Universidad Católica de Córdoba. Facultad de Ciencias Agropecuarias; ArgentinaFil: Nava, Santiago. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IDICAL); ArgentinaFil: Nava, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación de la Cadena Láctea (IDICAL); ArgentinaFil: Nava, Santiago. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; ArgentinaSpringer2026-10-15T15:50:50Z2026-10-15T15:50:50Z2026-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/28132https://link.springer.com/article/10.1007/s11250-026-05398-80049-47471573-7438https://doi.org/10.1007/s11250-026-05398-8Tropical Animal Health and Production 58 : article number 591. (October 2026)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repograntAgreement/INTA/2023-PE-L01-I044, Enfermedades subtropicales con impacto sobre la producción, salud pública y sustentabilidad en la ganadería del norte de Argentinainfo:eu-repo/semantics/restrictedAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)2026-11-05T11:51:40Zoai:localhost:20.500.12123/28132instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2026-11-05 11:51:41.01INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Use of pour-on formulations of fluralaner in prophylactic treatments against Cochliomyia hominivorax in newborn calves under extensive grazing systems
title Use of pour-on formulations of fluralaner in prophylactic treatments against Cochliomyia hominivorax in newborn calves under extensive grazing systems
spellingShingle Use of pour-on formulations of fluralaner in prophylactic treatments against Cochliomyia hominivorax in newborn calves under extensive grazing systems
Gamietea, Ignacio José
Ganado Bovino
Ternero
Parásitos
Miasis
Control de Enfermedades
Manejo de Parásitos
Ganadería Extensiva
Cattle
Calves
Cochliomyia hominivorax
Parasites
Myiasis
Diseases Control
Parasite Control
Extensive Husbandry
title_short Use of pour-on formulations of fluralaner in prophylactic treatments against Cochliomyia hominivorax in newborn calves under extensive grazing systems
title_full Use of pour-on formulations of fluralaner in prophylactic treatments against Cochliomyia hominivorax in newborn calves under extensive grazing systems
title_fullStr Use of pour-on formulations of fluralaner in prophylactic treatments against Cochliomyia hominivorax in newborn calves under extensive grazing systems
title_full_unstemmed Use of pour-on formulations of fluralaner in prophylactic treatments against Cochliomyia hominivorax in newborn calves under extensive grazing systems
title_sort Use of pour-on formulations of fluralaner in prophylactic treatments against Cochliomyia hominivorax in newborn calves under extensive grazing systems
dc.creator.none.fl_str_mv Gamietea, Ignacio José
Rossner, Maria Victoria
Lifschitz, Adrian Luis
Anziani, Oscar Sergio
Nava, Santiago
author Gamietea, Ignacio José
author_facet Gamietea, Ignacio José
Rossner, Maria Victoria
Lifschitz, Adrian Luis
Anziani, Oscar Sergio
Nava, Santiago
author_role author
author2 Rossner, Maria Victoria
Lifschitz, Adrian Luis
Anziani, Oscar Sergio
Nava, Santiago
author2_role author
author
author
author
dc.subject.none.fl_str_mv Ganado Bovino
Ternero
Parásitos
Miasis
Control de Enfermedades
Manejo de Parásitos
Ganadería Extensiva
Cattle
Calves
Cochliomyia hominivorax
Parasites
Myiasis
Diseases Control
Parasite Control
Extensive Husbandry
topic Ganado Bovino
Ternero
Parásitos
Miasis
Control de Enfermedades
Manejo de Parásitos
Ganadería Extensiva
Cattle
Calves
Cochliomyia hominivorax
Parasites
Myiasis
Diseases Control
Parasite Control
Extensive Husbandry
dc.description.none.fl_txt_mv The aim of this study was to evaluate the efficacy of pour-on fluralaner formulations for the prevention of cutaneous myiasis caused by Cochliomyia hominivorax in newborn calves under field conditions. Three field trials were conducted in Argentina, including subtropical and temperate regions. In Trial 1, calves with unhealed navels were assigned to two fluralaner-treated groups with different commercial pour-on formulations and an untreated control group. In Trial 2, two groups of newborn calves were treated either with fluralaner pour-on or injectable doramectin. Trial 3, where 84 calves were also treated with a pour-on formulation of fluralaner, was performed in an island livestock farming systems located along the Paraná River, where extensive grazing conditions are extreme, and the operational difficulties associated with providing meticulous animal husbandry practices to prevent parasitic diseases in cattle are amplified. Animals were monitored daily for the occurrence of myiasis. In Trial 1, no cases of myiasis were recorded in fluralaner-treated calves, whereas all control animals became infested. In Trial 2, no infestations were observed in the fluralaner-treated group, while myiasis was recorded in 3.5% of calves treated with doramectin. In Trial 3, the prevalence of myiasis in fluralaner-treated calves was 7.1%, with most cases associated with treatments applied under rainy conditions. In contrast, a prevalence of 34.5% was recorded in the previous year in the same herd when treatment consisted of insecticidal formulations based on organophosphates and pyrethroid. No adverse effects associated with fluralaner treatment were observed in all treated calves. These results demonstrate the high efficacy of fluralaner pour-on formulations for the prevention of C. hominivorax myiasis in newborn calves under extensive production systems.
EEA San Pedro
Fil: Gamietea, Ignacio José. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria San Pedro. Agencia de Extensión San Pedro; Argentina
Fil: Rossner, Maria Victoria. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Colonia Benitez; Argentina
Fil: Lifschitz, Adrian. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Centro de Investigación Veterinaria de Tandil (CIVETAN). Laboratorio de Farmacología; Argentina.
Fil: Lifschitz, Adrian. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro de Investigación Veterinaria de Tandil (CIVETAN); Argentina
Fil: Anziani, Oscar S. Universidad Católica de Córdoba. Facultad de Ciencias Agropecuarias; Argentina
Fil: Nava, Santiago. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela. Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina
Fil: Nava, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigación de la Cadena Láctea (IDICAL); Argentina
Fil: Nava, Santiago. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Rafaela; Argentina
description The aim of this study was to evaluate the efficacy of pour-on fluralaner formulations for the prevention of cutaneous myiasis caused by Cochliomyia hominivorax in newborn calves under field conditions. Three field trials were conducted in Argentina, including subtropical and temperate regions. In Trial 1, calves with unhealed navels were assigned to two fluralaner-treated groups with different commercial pour-on formulations and an untreated control group. In Trial 2, two groups of newborn calves were treated either with fluralaner pour-on or injectable doramectin. Trial 3, where 84 calves were also treated with a pour-on formulation of fluralaner, was performed in an island livestock farming systems located along the Paraná River, where extensive grazing conditions are extreme, and the operational difficulties associated with providing meticulous animal husbandry practices to prevent parasitic diseases in cattle are amplified. Animals were monitored daily for the occurrence of myiasis. In Trial 1, no cases of myiasis were recorded in fluralaner-treated calves, whereas all control animals became infested. In Trial 2, no infestations were observed in the fluralaner-treated group, while myiasis was recorded in 3.5% of calves treated with doramectin. In Trial 3, the prevalence of myiasis in fluralaner-treated calves was 7.1%, with most cases associated with treatments applied under rainy conditions. In contrast, a prevalence of 34.5% was recorded in the previous year in the same herd when treatment consisted of insecticidal formulations based on organophosphates and pyrethroid. No adverse effects associated with fluralaner treatment were observed in all treated calves. These results demonstrate the high efficacy of fluralaner pour-on formulations for the prevention of C. hominivorax myiasis in newborn calves under extensive production systems.
publishDate 2026
dc.date.none.fl_str_mv 2026-10-15T15:50:50Z
2026-10-15T15:50:50Z
2026-10
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/28132
https://link.springer.com/article/10.1007/s11250-026-05398-8
0049-4747
1573-7438
https://doi.org/10.1007/s11250-026-05398-8
url http://hdl.handle.net/20.500.12123/28132
https://link.springer.com/article/10.1007/s11250-026-05398-8
https://doi.org/10.1007/s11250-026-05398-8
identifier_str_mv 0049-4747
1573-7438
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repograntAgreement/INTA/2023-PE-L01-I044, Enfermedades subtropicales con impacto sobre la producción, salud pública y sustentabilidad en la ganadería del norte de Argentina
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv restrictedAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv Tropical Animal Health and Production 58 : article number 591. (October 2026)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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