Diagnostic challenge in Veterinary Pathology: Progressive neurological disease in Aberdeen Angus calves in Argentina

Autores
Sosa, Emiliano; Llada, Ignacio Mariano; Odriozola, Ernesto Raul; Fiorani, Franco; Quiroga, Alejandra; Morrell, Eleonora Lidia; Canton, German Jose
Año de publicación
2026
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
Clinical History, Laboratory Results, and Gross Findings: Aberdeen Angus calves from a beef production farm located in Balcarce (37°43′56″S, 58°24′43″W), Buenos Aires province, Argentina, developed a chronic, progressive neurologic syndrome. The cases occurred in a cow–calf herd that was largely closed for more than 15 years, with replacement heifers sourced internally and only occasional introduction of outside breeding bulls. Over a period of approximately 3 years, six 4- to 6-month-old nursing calves in good body condition exhibited progressive neurologic signs. In 2016, one calf developed chronic neurologic signs and died after several weeks. In 2017, 4 additional nursing calves in good body condition died after developing similar clinical signs. In some animals, excessive salivation and limb rigidity were noted by farm personnel. The clinical course progressed over several weeks, culminating in recumbency and either spontaneous death or euthanasia. Empirical treatments, including antibiotics and anti-inflammatory drugs, were administered in some cases but failed to produce clinical improvement. In April 2018, another 6-month-old calf presented with progressive neurologic signs characterized by depression, reduced appetite, reluctance to move, progressive ataxia, postural instability, worsening incoordination when stimulated or forced to move, and generalized limb paresis. This prompted veterinary consultation, and upon clinical examination of the animal, a decision was made to euthanize the calf for diagnostic investigation. The subsequent gross examination revealed no significant lesions in the brain, spinal cord, or other major organs.
EEA Balcarce
Fil: Sosa, Emiliano. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina
Fil: Llada, Ignacio. University of Georgia; Estados Unidos
Fil: Odriozola, Ernesto. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina
Fil: Fiorani, Franco. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina
Fil: Quiroga, Alejandra. Universidad Nacional de La Plata; Argentina
Fil: Morrell, Eleonora Lidia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina
Fil: Cantón, Germán José. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina
Fuente
Veterinary Pathology : ‍1-4 (26 August 2026)
Materia
Patología
Ganado Bovino
Diagnóstico
Enfermedades de los Animales
Pathology
Cattle
Diagnosis
Animal Diseases
Breeds (animal)
Razas (animales)
Argentina
Raza Aberdeen Angus
Nivel de accesibilidad
acceso restringido
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
INTA Digital (INTA)
Institución
Instituto Nacional de Tecnología Agropecuaria
OAI Identificador
oai:localhost:20.500.12123/27602
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oai_identifier_str oai:localhost:20.500.12123/27602
network_acronym_str INTADig
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network_name_str INTA Digital (INTA)
spelling Diagnostic challenge in Veterinary Pathology: Progressive neurological disease in Aberdeen Angus calves in ArgentinaSosa, EmilianoLlada, Ignacio MarianoOdriozola, Ernesto RaulFiorani, FrancoQuiroga, AlejandraMorrell, Eleonora LidiaCanton, German JosePatologíaGanado BovinoDiagnósticoEnfermedades de los AnimalesPathologyCattleDiagnosisAnimal DiseasesBreeds (animal)Razas (animales)ArgentinaRaza Aberdeen AngusClinical History, Laboratory Results, and Gross Findings: Aberdeen Angus calves from a beef production farm located in Balcarce (37°43′56″S, 58°24′43″W), Buenos Aires province, Argentina, developed a chronic, progressive neurologic syndrome. The cases occurred in a cow–calf herd that was largely closed for more than 15 years, with replacement heifers sourced internally and only occasional introduction of outside breeding bulls. Over a period of approximately 3 years, six 4- to 6-month-old nursing calves in good body condition exhibited progressive neurologic signs. In 2016, one calf developed chronic neurologic signs and died after several weeks. In 2017, 4 additional nursing calves in good body condition died after developing similar clinical signs. In some animals, excessive salivation and limb rigidity were noted by farm personnel. The clinical course progressed over several weeks, culminating in recumbency and either spontaneous death or euthanasia. Empirical treatments, including antibiotics and anti-inflammatory drugs, were administered in some cases but failed to produce clinical improvement. In April 2018, another 6-month-old calf presented with progressive neurologic signs characterized by depression, reduced appetite, reluctance to move, progressive ataxia, postural instability, worsening incoordination when stimulated or forced to move, and generalized limb paresis. This prompted veterinary consultation, and upon clinical examination of the animal, a decision was made to euthanize the calf for diagnostic investigation. The subsequent gross examination revealed no significant lesions in the brain, spinal cord, or other major organs.EEA BalcarceFil: Sosa, Emiliano. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; ArgentinaFil: Llada, Ignacio. University of Georgia; Estados UnidosFil: Odriozola, Ernesto. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; ArgentinaFil: Fiorani, Franco. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; ArgentinaFil: Quiroga, Alejandra. Universidad Nacional de La Plata; ArgentinaFil: Morrell, Eleonora Lidia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; ArgentinaFil: Cantón, Germán José. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; ArgentinaSAGE Publications2026-09-01T16:21:28Z2026-09-01T16:21:28Z2026-08-26info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdfhttp://hdl.handle.net/20.500.12123/27602https://journals.sagepub.com/doi/10.1177/03009858261480634300-9858 (print)1544-2217 (online)https://doi.org/10.1177/03009858261480634Veterinary Pathology : ‍1-4 (26 August 2026)reponame:INTA Digital (INTA)instname:Instituto Nacional de Tecnología Agropecuariaenginfo:eu-repograntAgreement/INTA/2019-RIST-E5-I111-001, Laboratorios de Diagnóstico Veterinarioinfo:eu-repo/semantics/restrictedAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)2026-09-24T11:43:45Zoai:localhost:20.500.12123/27602instacron:INTAInstitucionalhttp://repositorio.inta.gob.ar/Organismo científico-tecnológicoNo correspondehttp://repositorio.inta.gob.ar/oai/requesttripaldi.nicolas@inta.gob.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:l2026-09-24 11:43:46.401INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuariafalse
dc.title.none.fl_str_mv Diagnostic challenge in Veterinary Pathology: Progressive neurological disease in Aberdeen Angus calves in Argentina
title Diagnostic challenge in Veterinary Pathology: Progressive neurological disease in Aberdeen Angus calves in Argentina
spellingShingle Diagnostic challenge in Veterinary Pathology: Progressive neurological disease in Aberdeen Angus calves in Argentina
Sosa, Emiliano
Patología
Ganado Bovino
Diagnóstico
Enfermedades de los Animales
Pathology
Cattle
Diagnosis
Animal Diseases
Breeds (animal)
Razas (animales)
Argentina
Raza Aberdeen Angus
title_short Diagnostic challenge in Veterinary Pathology: Progressive neurological disease in Aberdeen Angus calves in Argentina
title_full Diagnostic challenge in Veterinary Pathology: Progressive neurological disease in Aberdeen Angus calves in Argentina
title_fullStr Diagnostic challenge in Veterinary Pathology: Progressive neurological disease in Aberdeen Angus calves in Argentina
title_full_unstemmed Diagnostic challenge in Veterinary Pathology: Progressive neurological disease in Aberdeen Angus calves in Argentina
title_sort Diagnostic challenge in Veterinary Pathology: Progressive neurological disease in Aberdeen Angus calves in Argentina
dc.creator.none.fl_str_mv Sosa, Emiliano
Llada, Ignacio Mariano
Odriozola, Ernesto Raul
Fiorani, Franco
Quiroga, Alejandra
Morrell, Eleonora Lidia
Canton, German Jose
author Sosa, Emiliano
author_facet Sosa, Emiliano
Llada, Ignacio Mariano
Odriozola, Ernesto Raul
Fiorani, Franco
Quiroga, Alejandra
Morrell, Eleonora Lidia
Canton, German Jose
author_role author
author2 Llada, Ignacio Mariano
Odriozola, Ernesto Raul
Fiorani, Franco
Quiroga, Alejandra
Morrell, Eleonora Lidia
Canton, German Jose
author2_role author
author
author
author
author
author
dc.subject.none.fl_str_mv Patología
Ganado Bovino
Diagnóstico
Enfermedades de los Animales
Pathology
Cattle
Diagnosis
Animal Diseases
Breeds (animal)
Razas (animales)
Argentina
Raza Aberdeen Angus
topic Patología
Ganado Bovino
Diagnóstico
Enfermedades de los Animales
Pathology
Cattle
Diagnosis
Animal Diseases
Breeds (animal)
Razas (animales)
Argentina
Raza Aberdeen Angus
dc.description.none.fl_txt_mv Clinical History, Laboratory Results, and Gross Findings: Aberdeen Angus calves from a beef production farm located in Balcarce (37°43′56″S, 58°24′43″W), Buenos Aires province, Argentina, developed a chronic, progressive neurologic syndrome. The cases occurred in a cow–calf herd that was largely closed for more than 15 years, with replacement heifers sourced internally and only occasional introduction of outside breeding bulls. Over a period of approximately 3 years, six 4- to 6-month-old nursing calves in good body condition exhibited progressive neurologic signs. In 2016, one calf developed chronic neurologic signs and died after several weeks. In 2017, 4 additional nursing calves in good body condition died after developing similar clinical signs. In some animals, excessive salivation and limb rigidity were noted by farm personnel. The clinical course progressed over several weeks, culminating in recumbency and either spontaneous death or euthanasia. Empirical treatments, including antibiotics and anti-inflammatory drugs, were administered in some cases but failed to produce clinical improvement. In April 2018, another 6-month-old calf presented with progressive neurologic signs characterized by depression, reduced appetite, reluctance to move, progressive ataxia, postural instability, worsening incoordination when stimulated or forced to move, and generalized limb paresis. This prompted veterinary consultation, and upon clinical examination of the animal, a decision was made to euthanize the calf for diagnostic investigation. The subsequent gross examination revealed no significant lesions in the brain, spinal cord, or other major organs.
EEA Balcarce
Fil: Sosa, Emiliano. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina
Fil: Llada, Ignacio. University of Georgia; Estados Unidos
Fil: Odriozola, Ernesto. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina
Fil: Fiorani, Franco. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias; Argentina
Fil: Quiroga, Alejandra. Universidad Nacional de La Plata; Argentina
Fil: Morrell, Eleonora Lidia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina
Fil: Cantón, Germán José. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Balcarce. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible; Argentina
description Clinical History, Laboratory Results, and Gross Findings: Aberdeen Angus calves from a beef production farm located in Balcarce (37°43′56″S, 58°24′43″W), Buenos Aires province, Argentina, developed a chronic, progressive neurologic syndrome. The cases occurred in a cow–calf herd that was largely closed for more than 15 years, with replacement heifers sourced internally and only occasional introduction of outside breeding bulls. Over a period of approximately 3 years, six 4- to 6-month-old nursing calves in good body condition exhibited progressive neurologic signs. In 2016, one calf developed chronic neurologic signs and died after several weeks. In 2017, 4 additional nursing calves in good body condition died after developing similar clinical signs. In some animals, excessive salivation and limb rigidity were noted by farm personnel. The clinical course progressed over several weeks, culminating in recumbency and either spontaneous death or euthanasia. Empirical treatments, including antibiotics and anti-inflammatory drugs, were administered in some cases but failed to produce clinical improvement. In April 2018, another 6-month-old calf presented with progressive neurologic signs characterized by depression, reduced appetite, reluctance to move, progressive ataxia, postural instability, worsening incoordination when stimulated or forced to move, and generalized limb paresis. This prompted veterinary consultation, and upon clinical examination of the animal, a decision was made to euthanize the calf for diagnostic investigation. The subsequent gross examination revealed no significant lesions in the brain, spinal cord, or other major organs.
publishDate 2026
dc.date.none.fl_str_mv 2026-09-01T16:21:28Z
2026-09-01T16:21:28Z
2026-08-26
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12123/27602
https://journals.sagepub.com/doi/10.1177/03009858261480634
300-9858 (print)
1544-2217 (online)
https://doi.org/10.1177/03009858261480634
url http://hdl.handle.net/20.500.12123/27602
https://journals.sagepub.com/doi/10.1177/03009858261480634
https://doi.org/10.1177/03009858261480634
identifier_str_mv 300-9858 (print)
1544-2217 (online)
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repograntAgreement/INTA/2019-RIST-E5-I111-001, Laboratorios de Diagnóstico Veterinario
dc.rights.none.fl_str_mv info:eu-repo/semantics/restrictedAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv restrictedAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv SAGE Publications
publisher.none.fl_str_mv SAGE Publications
dc.source.none.fl_str_mv Veterinary Pathology : ‍1-4 (26 August 2026)
reponame:INTA Digital (INTA)
instname:Instituto Nacional de Tecnología Agropecuaria
reponame_str INTA Digital (INTA)
collection INTA Digital (INTA)
instname_str Instituto Nacional de Tecnología Agropecuaria
repository.name.fl_str_mv INTA Digital (INTA) - Instituto Nacional de Tecnología Agropecuaria
repository.mail.fl_str_mv tripaldi.nicolas@inta.gob.ar
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