RXR expression in marine gastropods with different sensitivity to imposex development

Autores
Giulianelli, Sebastián; Primost, Mónica A.; Lanari, Claudia; Bigatti, Gregorio
Año de publicación
2020
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The superposition of male sexual characteristics in female marine gastropods (imposex) represents one of the clearest ecological examples of organotin-mediated endocrine disruption. Recent evidences suggest that signaling pathways mediated by members of the nuclear receptor superfamily, RXR and PPARγ, are involved in the development of this pseudohermaphroditic condition. Here, we identifed signifcant diferences in RXR expression in two caenogastropod species from Nuevo Gulf, Argentina, Buccinanops globulosus and Trophon geversianus, which present clear contrast in imposex incidence. In addition, B. globulosus males from a polluted and an unpolluted area showed diferences in RXR expression. Conversely, PPARγ levels were similar between both analyzed species. These fndings indicate specie-specifc RXR and PPARγ expression, suggesting a major role of RXR in the induction of imposex.
Fil: Giulianelli, Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico. Centro Nacional Patagónico. Instituto de Biología de Organismos Marinos; Argentina
Fil: Primost. Mónica. A. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico. Centro Nacional Patagónico. Instituto de Biología de Organismos Marinos; Argentina
Fil: Lanari, Claudia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental; Argentina.
Fil: Bigatti, Gregorio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico. Centro Nacional Patagónico. Instituto de Biología de Organismos Marinos; Argentina
Fil: Giulianelli, Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental; Argentina.
Fil: Primost. Mónica. A. Universidad Tecnológica Nacional. Facultad Regional Chubut. Grupo de Investigación y Desarrollo Tecnológico en Acuicultura y Pesca; Argentina.
Fil: Bigatti, Gregorio. Universidad Nacional de la Patagonia San Juan Bosco; Argentina
Fil: Bigatti, Gregorio. Universidad Espíritu Santo; Ecuador
Peer Reviewed
Fuente
Scientific Reports: 1-8. (2020)
Materia
Marine gastropods
Endocrine
Nivel de accesibilidad
acceso abierto
Condiciones de uso
2022-04-19T19:29:41Z
Repositorio
Repositorio Institucional Abierto (UTN)
Institución
Universidad Tecnológica Nacional
OAI Identificador
oai:ria.utn.edu.ar:20.500.12272/6154
Acceder
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network_name_str Repositorio Institucional Abierto (UTN)
spelling RXR expression in marine gastropods with different sensitivity to imposex developmentGiulianelli, SebastiánPrimost, Mónica A.Lanari, ClaudiaBigatti, GregorioMarine gastropodsEndocrineThe superposition of male sexual characteristics in female marine gastropods (imposex) represents one of the clearest ecological examples of organotin-mediated endocrine disruption. Recent evidences suggest that signaling pathways mediated by members of the nuclear receptor superfamily, RXR and PPARγ, are involved in the development of this pseudohermaphroditic condition. Here, we identifed signifcant diferences in RXR expression in two caenogastropod species from Nuevo Gulf, Argentina, Buccinanops globulosus and Trophon geversianus, which present clear contrast in imposex incidence. In addition, B. globulosus males from a polluted and an unpolluted area showed diferences in RXR expression. Conversely, PPARγ levels were similar between both analyzed species. These fndings indicate specie-specifc RXR and PPARγ expression, suggesting a major role of RXR in the induction of imposex.Fil: Giulianelli, Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico. Centro Nacional Patagónico. Instituto de Biología de Organismos Marinos; ArgentinaFil: Primost. Mónica. A. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico. Centro Nacional Patagónico. Instituto de Biología de Organismos Marinos; ArgentinaFil: Lanari, Claudia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental; Argentina.Fil: Bigatti, Gregorio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico. Centro Nacional Patagónico. Instituto de Biología de Organismos Marinos; ArgentinaFil: Giulianelli, Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental; Argentina.Fil: Primost. Mónica. A. Universidad Tecnológica Nacional. Facultad Regional Chubut. Grupo de Investigación y Desarrollo Tecnológico en Acuicultura y Pesca; Argentina.Fil: Bigatti, Gregorio. Universidad Nacional de la Patagonia San Juan Bosco; ArgentinaFil: Bigatti, Gregorio. Universidad Espíritu Santo; EcuadorPeer ReviewedNature2022-04-19T19:29:41Z2022-04-19T19:29:41Z2020-06-11info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articulopdfapplication/pdfhttps://doi.org/10.1038/s41598-020-66402-1http://hdl.handle.net/20.500.12272/6154Scientific Reports: 1-8. (2020)reponame:Repositorio Institucional Abierto (UTN)instname:Universidad Tecnológica Nacionalenginfo:eu-repo/semantics/openAccess2022-04-19T19:29:41Zhttp://creativecommons.org/licenses/by-nc-nd/4.0/Attribution-NonCommercial-NoDerivatives 4.0 InternacionalCreative commons2026-09-24T12:44:38Zoai:ria.utn.edu.ar:20.500.12272/6154instacron:UTNInstitucionalhttp://ria.utn.edu.ar/Universidad públicaNo correspondehttp://ria.utn.edu.ar/oaigestionria@rec.utn.edu.ar; fsuarez@rec.utn.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:a2026-09-24 12:44:40.122Repositorio Institucional Abierto (UTN) - Universidad Tecnológica Nacionalfalse
dc.title.none.fl_str_mv RXR expression in marine gastropods with different sensitivity to imposex development
title RXR expression in marine gastropods with different sensitivity to imposex development
spellingShingle RXR expression in marine gastropods with different sensitivity to imposex development
Giulianelli, Sebastián
Marine gastropods
Endocrine
title_short RXR expression in marine gastropods with different sensitivity to imposex development
title_full RXR expression in marine gastropods with different sensitivity to imposex development
title_fullStr RXR expression in marine gastropods with different sensitivity to imposex development
title_full_unstemmed RXR expression in marine gastropods with different sensitivity to imposex development
title_sort RXR expression in marine gastropods with different sensitivity to imposex development
dc.creator.none.fl_str_mv Giulianelli, Sebastián
Primost, Mónica A.
Lanari, Claudia
Bigatti, Gregorio
author Giulianelli, Sebastián
author_facet Giulianelli, Sebastián
Primost, Mónica A.
Lanari, Claudia
Bigatti, Gregorio
author_role author
author2 Primost, Mónica A.
Lanari, Claudia
Bigatti, Gregorio
author2_role author
author
author
dc.subject.none.fl_str_mv Marine gastropods
Endocrine
topic Marine gastropods
Endocrine
dc.description.none.fl_txt_mv The superposition of male sexual characteristics in female marine gastropods (imposex) represents one of the clearest ecological examples of organotin-mediated endocrine disruption. Recent evidences suggest that signaling pathways mediated by members of the nuclear receptor superfamily, RXR and PPARγ, are involved in the development of this pseudohermaphroditic condition. Here, we identifed signifcant diferences in RXR expression in two caenogastropod species from Nuevo Gulf, Argentina, Buccinanops globulosus and Trophon geversianus, which present clear contrast in imposex incidence. In addition, B. globulosus males from a polluted and an unpolluted area showed diferences in RXR expression. Conversely, PPARγ levels were similar between both analyzed species. These fndings indicate specie-specifc RXR and PPARγ expression, suggesting a major role of RXR in the induction of imposex.
Fil: Giulianelli, Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico. Centro Nacional Patagónico. Instituto de Biología de Organismos Marinos; Argentina
Fil: Primost. Mónica. A. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico. Centro Nacional Patagónico. Instituto de Biología de Organismos Marinos; Argentina
Fil: Lanari, Claudia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental; Argentina.
Fil: Bigatti, Gregorio. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico. Centro Nacional Patagónico. Instituto de Biología de Organismos Marinos; Argentina
Fil: Giulianelli, Sebastián. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental; Argentina.
Fil: Primost. Mónica. A. Universidad Tecnológica Nacional. Facultad Regional Chubut. Grupo de Investigación y Desarrollo Tecnológico en Acuicultura y Pesca; Argentina.
Fil: Bigatti, Gregorio. Universidad Nacional de la Patagonia San Juan Bosco; Argentina
Fil: Bigatti, Gregorio. Universidad Espíritu Santo; Ecuador
Peer Reviewed
description The superposition of male sexual characteristics in female marine gastropods (imposex) represents one of the clearest ecological examples of organotin-mediated endocrine disruption. Recent evidences suggest that signaling pathways mediated by members of the nuclear receptor superfamily, RXR and PPARγ, are involved in the development of this pseudohermaphroditic condition. Here, we identifed signifcant diferences in RXR expression in two caenogastropod species from Nuevo Gulf, Argentina, Buccinanops globulosus and Trophon geversianus, which present clear contrast in imposex incidence. In addition, B. globulosus males from a polluted and an unpolluted area showed diferences in RXR expression. Conversely, PPARγ levels were similar between both analyzed species. These fndings indicate specie-specifc RXR and PPARγ expression, suggesting a major role of RXR in the induction of imposex.
publishDate 2020
dc.date.none.fl_str_mv 2020-06-11
2022-04-19T19:29:41Z
2022-04-19T19:29:41Z
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.1038/s41598-020-66402-1
http://hdl.handle.net/20.500.12272/6154
url https://doi.org/10.1038/s41598-020-66402-1
http://hdl.handle.net/20.500.12272/6154
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
2022-04-19T19:29:41Z
http://creativecommons.org/licenses/by-nc-nd/4.0/
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Creative commons
eu_rights_str_mv openAccess
rights_invalid_str_mv 2022-04-19T19:29:41Z
http://creativecommons.org/licenses/by-nc-nd/4.0/
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
Creative commons
dc.format.none.fl_str_mv pdf
application/pdf
dc.publisher.none.fl_str_mv Nature
publisher.none.fl_str_mv Nature
dc.source.none.fl_str_mv Scientific Reports: 1-8. (2020)
reponame:Repositorio Institucional Abierto (UTN)
instname:Universidad Tecnológica Nacional
reponame_str Repositorio Institucional Abierto (UTN)
collection Repositorio Institucional Abierto (UTN)
instname_str Universidad Tecnológica Nacional
repository.name.fl_str_mv Repositorio Institucional Abierto (UTN) - Universidad Tecnológica Nacional
repository.mail.fl_str_mv gestionria@rec.utn.edu.ar; fsuarez@rec.utn.edu.ar
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