Phytochemical profile and anti-Inflammatory effect of the orchid <i>Catasetum macroglossum</i>

Autores
Consolini, Alicia Elvira; Spegazzini, Etile Dolores; Debenedetti, Silvia Laura; Rosella, María Adelaida; Colareda, Germán Andrés; Ramos, Pablo
Año de publicación
2012
Idioma
inglés
Tipo de recurso
artículo
Estado
versión publicada
Descripción
The pseudobulbs of Catasetum macroglossum (Orchidaceae) are popularly used as topical anti-inflammatory and antirheumatic in the forests and medium lands of Ecuador, but they were never studied. We evaluated whether the decoction of C. macroglossum has antiinflammatory effect and which is its phytochemical profile. The effect of 30 and 90 mg lyophilized/kg via i.p. was studied on the carrageenaninduced edema in the paw rat, in comparison with saline and indomethacin. The paw edema was inhibited in about 60 to 80 % after 1 to 3 h of carrageenan injection. The phytochemical profile was done by chemical tests to evaluate the presence of reducing sugars and flavonoids, and TLC of the aqueous extract and the hydrolyzed one. There were detected reductive substances after the acidic hydrolysis, and two spots with the features and Rf of the standard glucose and mannose. Some peaks in the HPLC-DAD chromatogram showed absorption at 225 and 280 nm in agreement with dihydro derivatives of phenantrene and stilbene in traces amount. The antiinflammatory kinetic of C. macroglossum suggests inhibition on prostaglandins. This work validates the popular use of C. macroglossum, which could be due to the presence of a glucomannan and traces of phenantrene and stilbene, as in other species of Catasetum.
Colegio de Farmacéuticos de la Provincia de Buenos Aires
Materia
Farmacia
Catasetum macroglossum;
HPLC-DAD
TLC
Nivel de accesibilidad
acceso abierto
Condiciones de uso
http://creativecommons.org/licenses/by-nc-sa/4.0/
Repositorio
SEDICI (UNLP)
Institución
Universidad Nacional de La Plata
OAI Identificador
oai:sedici.unlp.edu.ar:10915/8430
Acceder
id SEDICI_21d2fb5b7f44cc7994be162393248b7b
oai_identifier_str oai:sedici.unlp.edu.ar:10915/8430
network_acronym_str SEDICI
repository_id_str 1329
network_name_str SEDICI (UNLP)
spelling Phytochemical profile and anti-Inflammatory effect of the orchid <i>Catasetum macroglossum</i>Consolini, Alicia ElviraSpegazzini, Etile DoloresDebenedetti, Silvia LauraRosella, María AdelaidaColareda, Germán AndrésRamos, PabloFarmaciaCatasetum macroglossum;HPLC-DADTLCThe pseudobulbs of Catasetum macroglossum (Orchidaceae) are popularly used as topical anti-inflammatory and antirheumatic in the forests and medium lands of Ecuador, but they were never studied. We evaluated whether the decoction of C. macroglossum has antiinflammatory effect and which is its phytochemical profile. The effect of 30 and 90 mg lyophilized/kg via i.p. was studied on the carrageenaninduced edema in the paw rat, in comparison with saline and indomethacin. The paw edema was inhibited in about 60 to 80 % after 1 to 3 h of carrageenan injection. The phytochemical profile was done by chemical tests to evaluate the presence of reducing sugars and flavonoids, and TLC of the aqueous extract and the hydrolyzed one. There were detected reductive substances after the acidic hydrolysis, and two spots with the features and Rf of the standard glucose and mannose. Some peaks in the HPLC-DAD chromatogram showed absorption at 225 and 280 nm in agreement with dihydro derivatives of phenantrene and stilbene in traces amount. The antiinflammatory kinetic of C. macroglossum suggests inhibition on prostaglandins. This work validates the popular use of C. macroglossum, which could be due to the presence of a glucomannan and traces of phenantrene and stilbene, as in other species of Catasetum.Colegio de Farmacéuticos de la Provincia de Buenos Aires2012info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticulohttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articuloapplication/pdf62-67http://sedici.unlp.edu.ar/handle/10915/8430enginfo:eu-repo/semantics/altIdentifier/url/http://www.latamjpharm.org/resumenes/31/1/LAJOP_31_1_1_10.pdfinfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-sa/4.0/Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)reponame:SEDICI (UNLP)instname:Universidad Nacional de La Platainstacron:UNLP2026-06-23T10:13:09Zoai:sedici.unlp.edu.ar:10915/8430Institucionalhttp://sedici.unlp.edu.ar/Universidad públicaNo correspondehttp://sedici.unlp.edu.ar/oai/snrdalira@sedici.unlp.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:13292026-06-23 10:13:09.335SEDICI (UNLP) - Universidad Nacional de La Platafalse
dc.title.none.fl_str_mv Phytochemical profile and anti-Inflammatory effect of the orchid <i>Catasetum macroglossum</i>
title Phytochemical profile and anti-Inflammatory effect of the orchid <i>Catasetum macroglossum</i>
spellingShingle Phytochemical profile and anti-Inflammatory effect of the orchid <i>Catasetum macroglossum</i>
Consolini, Alicia Elvira
Farmacia
Catasetum macroglossum;
HPLC-DAD
TLC
title_short Phytochemical profile and anti-Inflammatory effect of the orchid <i>Catasetum macroglossum</i>
title_full Phytochemical profile and anti-Inflammatory effect of the orchid <i>Catasetum macroglossum</i>
title_fullStr Phytochemical profile and anti-Inflammatory effect of the orchid <i>Catasetum macroglossum</i>
title_full_unstemmed Phytochemical profile and anti-Inflammatory effect of the orchid <i>Catasetum macroglossum</i>
title_sort Phytochemical profile and anti-Inflammatory effect of the orchid <i>Catasetum macroglossum</i>
dc.creator.none.fl_str_mv Consolini, Alicia Elvira
Spegazzini, Etile Dolores
Debenedetti, Silvia Laura
Rosella, María Adelaida
Colareda, Germán Andrés
Ramos, Pablo
author Consolini, Alicia Elvira
author_facet Consolini, Alicia Elvira
Spegazzini, Etile Dolores
Debenedetti, Silvia Laura
Rosella, María Adelaida
Colareda, Germán Andrés
Ramos, Pablo
author_role author
author2 Spegazzini, Etile Dolores
Debenedetti, Silvia Laura
Rosella, María Adelaida
Colareda, Germán Andrés
Ramos, Pablo
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Farmacia
Catasetum macroglossum;
HPLC-DAD
TLC
topic Farmacia
Catasetum macroglossum;
HPLC-DAD
TLC
dc.description.none.fl_txt_mv The pseudobulbs of Catasetum macroglossum (Orchidaceae) are popularly used as topical anti-inflammatory and antirheumatic in the forests and medium lands of Ecuador, but they were never studied. We evaluated whether the decoction of C. macroglossum has antiinflammatory effect and which is its phytochemical profile. The effect of 30 and 90 mg lyophilized/kg via i.p. was studied on the carrageenaninduced edema in the paw rat, in comparison with saline and indomethacin. The paw edema was inhibited in about 60 to 80 % after 1 to 3 h of carrageenan injection. The phytochemical profile was done by chemical tests to evaluate the presence of reducing sugars and flavonoids, and TLC of the aqueous extract and the hydrolyzed one. There were detected reductive substances after the acidic hydrolysis, and two spots with the features and Rf of the standard glucose and mannose. Some peaks in the HPLC-DAD chromatogram showed absorption at 225 and 280 nm in agreement with dihydro derivatives of phenantrene and stilbene in traces amount. The antiinflammatory kinetic of C. macroglossum suggests inhibition on prostaglandins. This work validates the popular use of C. macroglossum, which could be due to the presence of a glucomannan and traces of phenantrene and stilbene, as in other species of Catasetum.
Colegio de Farmacéuticos de la Provincia de Buenos Aires
description The pseudobulbs of Catasetum macroglossum (Orchidaceae) are popularly used as topical anti-inflammatory and antirheumatic in the forests and medium lands of Ecuador, but they were never studied. We evaluated whether the decoction of C. macroglossum has antiinflammatory effect and which is its phytochemical profile. The effect of 30 and 90 mg lyophilized/kg via i.p. was studied on the carrageenaninduced edema in the paw rat, in comparison with saline and indomethacin. The paw edema was inhibited in about 60 to 80 % after 1 to 3 h of carrageenan injection. The phytochemical profile was done by chemical tests to evaluate the presence of reducing sugars and flavonoids, and TLC of the aqueous extract and the hydrolyzed one. There were detected reductive substances after the acidic hydrolysis, and two spots with the features and Rf of the standard glucose and mannose. Some peaks in the HPLC-DAD chromatogram showed absorption at 225 and 280 nm in agreement with dihydro derivatives of phenantrene and stilbene in traces amount. The antiinflammatory kinetic of C. macroglossum suggests inhibition on prostaglandins. This work validates the popular use of C. macroglossum, which could be due to the presence of a glucomannan and traces of phenantrene and stilbene, as in other species of Catasetum.
publishDate 2012
dc.date.none.fl_str_mv 2012
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Articulo
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://sedici.unlp.edu.ar/handle/10915/8430
url http://sedici.unlp.edu.ar/handle/10915/8430
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv info:eu-repo/semantics/altIdentifier/url/http://www.latamjpharm.org/resumenes/31/1/LAJOP_31_1_1_10.pdf
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/4.0/
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0)
dc.format.none.fl_str_mv application/pdf
62-67
dc.source.none.fl_str_mv reponame:SEDICI (UNLP)
instname:Universidad Nacional de La Plata
instacron:UNLP
reponame_str SEDICI (UNLP)
collection SEDICI (UNLP)
instname_str Universidad Nacional de La Plata
instacron_str UNLP
institution UNLP
repository.name.fl_str_mv SEDICI (UNLP) - Universidad Nacional de La Plata
repository.mail.fl_str_mv alira@sedici.unlp.edu.ar
_version_ 1868981601488076800
score 13.364332

Publicaciones similares