Validity of capillary imbibition models in paper-based microfluidic applications

Autores
Gerlero, Gabriel S.; Valdéz, Andrés R.; Urteaga, Raúl; Kler, Pablo A.
Año de publicación
2022
Idioma
inglés
Tipo de recurso
artículo
Estado
versión borrador
Descripción
Paper-based microfluidics has grown continuously over the last few years. One of the most important characteristics of paper-based microfluidic devices is the ability to pump fluids with the single action of capillary forces. However, fluid flow control in paper-based microfluidic devices has been studied primarily through empirical approaches; and as paper-based microfluidic devices have become more complex, more general and precise models of fluid flow are required. Particularly difficult to model are unsaturated flow conditions, which are critical to the overall performance of paper-based analytical devices, which may contain pre-adsorbed reagents such as indicator particles or antibodies. In this work we propose an objective test and a discussion on the suitability of different models (including a novel model derived here from LET-based models) that represent fluid imbibition dynamics in paper substrates. We reproduce experimental fluid fronts with the best parameter fits of the different models to show their actual capabilities to represent the moisture content function and present an analysis of propagation of uncertainties to obtain a final objective quantification of the quality of model fits. This objective analysis will endow the paper-based microfluidics community with objective information about modeling tools to improve the designs and performance of these devices.
Fil: Kler, Pablo A. CONICET-UNL. Centro de Investigación en Métodos Computacionales (CIMEC); Argentina.
Fil: Gerlero, Gabriel S. CONICET-UNL. Centro de Investigación en Métodos Computacionales (CIMEC); Argentina.
Fil: Valdez, Andrés R. Federal University of Juiz de Fora. Computational Modeling Graduate Program; Brasil.
Fil: Urteaga, Raúl. CONICET-UNL. Instituto de Física del Litoral (IFIS Litoral); Argentina.
Fil: Kler, Pablo A. Universidad Tecnológica Nacional. Facultad Regional Santa Fe. Departamento de Ingeniería en Sistemas de Información; Argentina.
Peer Reviewed
Fuente
Transport in Porous Media, vol. 141: 359–378, (2022)
Materia
Unsaturated flow
Paper based microfluidics
Imbibition models
Boltzmann transformation
Whatman filter paper
Nivel de accesibilidad
acceso abierto
Condiciones de uso
2024-03-27T20:50:25Z
Repositorio
Repositorio Institucional Abierto (UTN)
Institución
Universidad Tecnológica Nacional
OAI Identificador
oai:ria.utn.edu.ar:20.500.12272/10232
Acceder
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network_acronym_str RIAUTN
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network_name_str Repositorio Institucional Abierto (UTN)
spelling Validity of capillary imbibition models in paper-based microfluidic applicationsGerlero, Gabriel S.Valdéz, Andrés R.Urteaga, RaúlKler, Pablo A.Unsaturated flowPaper based microfluidicsImbibition modelsBoltzmann transformationWhatman filter paperPaper-based microfluidics has grown continuously over the last few years. One of the most important characteristics of paper-based microfluidic devices is the ability to pump fluids with the single action of capillary forces. However, fluid flow control in paper-based microfluidic devices has been studied primarily through empirical approaches; and as paper-based microfluidic devices have become more complex, more general and precise models of fluid flow are required. Particularly difficult to model are unsaturated flow conditions, which are critical to the overall performance of paper-based analytical devices, which may contain pre-adsorbed reagents such as indicator particles or antibodies. In this work we propose an objective test and a discussion on the suitability of different models (including a novel model derived here from LET-based models) that represent fluid imbibition dynamics in paper substrates. We reproduce experimental fluid fronts with the best parameter fits of the different models to show their actual capabilities to represent the moisture content function and present an analysis of propagation of uncertainties to obtain a final objective quantification of the quality of model fits. This objective analysis will endow the paper-based microfluidics community with objective information about modeling tools to improve the designs and performance of these devices.Fil: Kler, Pablo A. CONICET-UNL. Centro de Investigación en Métodos Computacionales (CIMEC); Argentina.Fil: Gerlero, Gabriel S. CONICET-UNL. Centro de Investigación en Métodos Computacionales (CIMEC); Argentina.Fil: Valdez, Andrés R. Federal University of Juiz de Fora. Computational Modeling Graduate Program; Brasil.Fil: Urteaga, Raúl. CONICET-UNL. Instituto de Física del Litoral (IFIS Litoral); Argentina.Fil: Kler, Pablo A. Universidad Tecnológica Nacional. Facultad Regional Santa Fe. Departamento de Ingeniería en Sistemas de Información; Argentina.Peer Reviewed2024-03-27T20:50:25Z2024-03-27T20:50:25Z2022-01-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/drafthttp://purl.org/coar/resource_type/c_6501info:ar-repo/semantics/articulopdfapplication/pdfGerlero, G.S. et al. Validity of Capillary Imbibition Models in Paper-Based Microfluidic Applications. Transport in Porous Media, vol. 141: 359–378, (2022).http://hdl.handle.net/20.500.12272/1023210.1007/s11242-021-01724-wTransport in Porous Media, vol. 141: 359–378, (2022)reponame:Repositorio Institucional Abierto (UTN)instname:Universidad Tecnológica NacionalengASUTIFE0005525TC - Prototipos numéricos de alto desempeño computacional para flujo y transporte multifásico en aplicaciones ingenierilesinfo:eu-repo/semantics/openAccess2024-03-27T20:50:25Zhttp://creativecommons.org/licenses/by/4.0/Atribución 4.0 InternacionalLos autoresCreativeCommons2026-09-24T12:46:54Zoai:ria.utn.edu.ar:20.500.12272/10232instacron:UTNInstitucionalhttp://ria.utn.edu.ar/Universidad públicaNo correspondehttp://ria.utn.edu.ar/oaigestionria@rec.utn.edu.ar; fsuarez@rec.utn.edu.arArgentinaNo correspondeNo correspondeNo correspondeopendoar:a2026-09-24 12:46:55.433Repositorio Institucional Abierto (UTN) - Universidad Tecnológica Nacionalfalse
dc.title.none.fl_str_mv Validity of capillary imbibition models in paper-based microfluidic applications
title Validity of capillary imbibition models in paper-based microfluidic applications
spellingShingle Validity of capillary imbibition models in paper-based microfluidic applications
Gerlero, Gabriel S.
Unsaturated flow
Paper based microfluidics
Imbibition models
Boltzmann transformation
Whatman filter paper
title_short Validity of capillary imbibition models in paper-based microfluidic applications
title_full Validity of capillary imbibition models in paper-based microfluidic applications
title_fullStr Validity of capillary imbibition models in paper-based microfluidic applications
title_full_unstemmed Validity of capillary imbibition models in paper-based microfluidic applications
title_sort Validity of capillary imbibition models in paper-based microfluidic applications
dc.creator.none.fl_str_mv Gerlero, Gabriel S.
Valdéz, Andrés R.
Urteaga, Raúl
Kler, Pablo A.
author Gerlero, Gabriel S.
author_facet Gerlero, Gabriel S.
Valdéz, Andrés R.
Urteaga, Raúl
Kler, Pablo A.
author_role author
author2 Valdéz, Andrés R.
Urteaga, Raúl
Kler, Pablo A.
author2_role author
author
author
dc.subject.none.fl_str_mv Unsaturated flow
Paper based microfluidics
Imbibition models
Boltzmann transformation
Whatman filter paper
topic Unsaturated flow
Paper based microfluidics
Imbibition models
Boltzmann transformation
Whatman filter paper
dc.description.none.fl_txt_mv Paper-based microfluidics has grown continuously over the last few years. One of the most important characteristics of paper-based microfluidic devices is the ability to pump fluids with the single action of capillary forces. However, fluid flow control in paper-based microfluidic devices has been studied primarily through empirical approaches; and as paper-based microfluidic devices have become more complex, more general and precise models of fluid flow are required. Particularly difficult to model are unsaturated flow conditions, which are critical to the overall performance of paper-based analytical devices, which may contain pre-adsorbed reagents such as indicator particles or antibodies. In this work we propose an objective test and a discussion on the suitability of different models (including a novel model derived here from LET-based models) that represent fluid imbibition dynamics in paper substrates. We reproduce experimental fluid fronts with the best parameter fits of the different models to show their actual capabilities to represent the moisture content function and present an analysis of propagation of uncertainties to obtain a final objective quantification of the quality of model fits. This objective analysis will endow the paper-based microfluidics community with objective information about modeling tools to improve the designs and performance of these devices.
Fil: Kler, Pablo A. CONICET-UNL. Centro de Investigación en Métodos Computacionales (CIMEC); Argentina.
Fil: Gerlero, Gabriel S. CONICET-UNL. Centro de Investigación en Métodos Computacionales (CIMEC); Argentina.
Fil: Valdez, Andrés R. Federal University of Juiz de Fora. Computational Modeling Graduate Program; Brasil.
Fil: Urteaga, Raúl. CONICET-UNL. Instituto de Física del Litoral (IFIS Litoral); Argentina.
Fil: Kler, Pablo A. Universidad Tecnológica Nacional. Facultad Regional Santa Fe. Departamento de Ingeniería en Sistemas de Información; Argentina.
Peer Reviewed
description Paper-based microfluidics has grown continuously over the last few years. One of the most important characteristics of paper-based microfluidic devices is the ability to pump fluids with the single action of capillary forces. However, fluid flow control in paper-based microfluidic devices has been studied primarily through empirical approaches; and as paper-based microfluidic devices have become more complex, more general and precise models of fluid flow are required. Particularly difficult to model are unsaturated flow conditions, which are critical to the overall performance of paper-based analytical devices, which may contain pre-adsorbed reagents such as indicator particles or antibodies. In this work we propose an objective test and a discussion on the suitability of different models (including a novel model derived here from LET-based models) that represent fluid imbibition dynamics in paper substrates. We reproduce experimental fluid fronts with the best parameter fits of the different models to show their actual capabilities to represent the moisture content function and present an analysis of propagation of uncertainties to obtain a final objective quantification of the quality of model fits. This objective analysis will endow the paper-based microfluidics community with objective information about modeling tools to improve the designs and performance of these devices.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-04
2024-03-27T20:50:25Z
2024-03-27T20:50:25Z
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/draft
http://purl.org/coar/resource_type/c_6501
info:ar-repo/semantics/articulo
format article
status_str draft
dc.identifier.none.fl_str_mv Gerlero, G.S. et al. Validity of Capillary Imbibition Models in Paper-Based Microfluidic Applications. Transport in Porous Media, vol. 141: 359–378, (2022).
http://hdl.handle.net/20.500.12272/10232
10.1007/s11242-021-01724-w
identifier_str_mv Gerlero, G.S. et al. Validity of Capillary Imbibition Models in Paper-Based Microfluidic Applications. Transport in Porous Media, vol. 141: 359–378, (2022).
10.1007/s11242-021-01724-w
url http://hdl.handle.net/20.500.12272/10232
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv ASUTIFE0005525TC - Prototipos numéricos de alto desempeño computacional para flujo y transporte multifásico en aplicaciones ingenieriles
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
2024-03-27T20:50:25Z
http://creativecommons.org/licenses/by/4.0/
Atribución 4.0 Internacional
Los autores
CreativeCommons
eu_rights_str_mv openAccess
rights_invalid_str_mv 2024-03-27T20:50:25Z
http://creativecommons.org/licenses/by/4.0/
Atribución 4.0 Internacional
Los autores
CreativeCommons
dc.format.none.fl_str_mv pdf
application/pdf
dc.source.none.fl_str_mv Transport in Porous Media, vol. 141: 359–378, (2022)
reponame:Repositorio Institucional Abierto (UTN)
instname:Universidad Tecnológica Nacional
reponame_str Repositorio Institucional Abierto (UTN)
collection Repositorio Institucional Abierto (UTN)
instname_str Universidad Tecnológica Nacional
repository.name.fl_str_mv Repositorio Institucional Abierto (UTN) - Universidad Tecnológica Nacional
repository.mail.fl_str_mv gestionria@rec.utn.edu.ar; fsuarez@rec.utn.edu.ar
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score 13.24418

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